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Catalog Number: (77626-716)
Supplier: AMBEED, INC
Description: 8-Bromoadenosine-3',5'-cyclic monophosphate ≥99%

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Catalog Number: (10464-104)
Supplier: Bioss
Description: Lipin 1 is a member of the Lipin family of nuclear proteins. This family contains three members: Lipin 1, Lipin 2 and Lipin 3, all of which contain a nuclear signal sequence, a highly conserved amino-terminal (NLIP) domain and a carboxy-terminal (CLIP) domain. LPIN1 (Lipin 1) is crucial for normal adipose tissue development and metabolism. LPIN1 selectively activates a subset of PGC1 alpha target pathways, including fatty acid oxidation and mitochondrial oxidative phosphorylation by inducing expression of the nuclear receptor PPARalpha. LPIN1 also inactivates the lipogenic program and suppresses circulating lipid levels. An abundance of LPIN1 promotes fat accumulation and insulin sensitivity, whereas a deficiency in LPIN1 may deter normal adipose tissue development, resulting in insulin resistance and lipodystrophy, a heterogeneous group of disorders characterized by loss of body fat, fatty liver, hypertriglyceridemia and insulin resistance.


Supplier: MP Biomedicals
Description: Decane (n-Decane), an aliphatic hydrocarbon, is a reference fuel. Its oxidation over a range of temperature has been studied. Its crystal structure has been investigated at 150K. The cracking of decane can be performed using electrohydrodynamic atomization system (EHDA).
Decane has been used as a solvent in the preparation of high alkane phase emulsified suspensions (HAPES). It may also be used as a solvent to suspend the CdSe/ZnS nanocrystals during absorbance measurement. Internal standard in the GC analysis of oxalic, malonic, and succinic acids in biological materials.

Supplier: TCI America
Description: [Catalyst for Oxidation] CAS Number: 3225-26-1 MDL Number: MFCD00075563 Molecular Formula: C16H22NO3 Molecular Weight: 276.36 Purity/Analysis Method: <gt/>97.0% (GC) Form: Crystal Melting point (°C): 104

SDS

Catalog Number: (76011-034)
Supplier: Prosci
Description: SUMO4 is a member of the SUMO gene family. This family of small ubiquitin-related modifiers covalently modify target lysines in proteins and control the target proteins' subcellular localization, stability, or activity. Upon oxidative stress, SUMO4 conjugates to various anti-oxidant enzymes, chaperones, and stress defense proteins. This protein may also conjugate to NFKBIA, TFAP2A and FOS, negatively regulating their transcriptional activity, and to NR3C1, positively regulating its transcriptional activity. Covalent attachment to SUMO4 substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I. In contrast to SUMO1, SUMO2 and SUMO3, SUMO4 seems to be insensitive to sentrin-specific proteases due to the presence of Pro-90. This may impair processing to mature form and conjugation to substrates. SUMO4 is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. The M55V substitution has been associated with type I diabetes.


Supplier: Safety & Industrial Supplies
Description: The TorquePlus™ internal design minimizes fastener rounding, helps to extend fastener life, and allows the user to more easily turn worn, rounded or rusted fasteners.

Catalog Number: (10406-484)
Supplier: Bioss
Description: The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia. [provided by RefSeq].


Catalog Number: (76083-558)
Supplier: Bioss
Description: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34C expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.


Catalog Number: (10351-748)
Supplier: Bioss
Description: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.


Supplier: Thermo Scientific Chemicals
Description: MDL: MFCD00149166 Fieser: 1,1059 3,265
Catalog Number: (102964-872)
Supplier: Cell Biolabs
Description: OxiSelect™ Protein Carbonyl Immunoblot Kit provides a rapid, efficient method for the detection of protein carbonyl residues


Catalog Number: (10404-402)
Supplier: Bioss
Description: Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.


Supplier: BURKLE INC
Description: Delivery tubes made of PP are resistant against weak acids, caustic solutions and detergents.
Delivery tubes made of PVDF are especially for acids and caustic solutions; not for strongly oxidizing acids and caustic solutions.
Delivery tubes made of stainless steel 304 are for solvents and liquids of VbF Hazard Class AIII (not easily flammable).
Battery pump for safe filling of car batteries with acid or distilled water.

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Catalog Number: (97009-926)
Supplier: Lovibond
Description: Includes Citrate Buffer & Sodium Periodate Powder Packs. USEPA accepted for reporting wastewater analysis. Method: Periodate Oxidation;Range: 0.1 to 20.0 mg/L;suitable for use with Orbeco-Hellige & other colorimeters/spectrophotometers

Small Business Enterprise


Supplier: Shenandoah Biotechnology
Description: Leptin is a hormone that is produced by adipose tissue and plays critical roles in the physiologic regulation of body weight. Leptin acts through the leptin receptor (LEPR) to regulate adipose mass by inhibiting hunger and balancing energy usage. Leptin mutations cause severe hereditary obesity and hypogonadism in rodents and humans. Leptin also has thermogenic actions, regulates enzymes of fatty acid oxidation, and is involved in hematopoiesis, angiogenesis, wound healing, inflammation, and immune responses.

Catalog Number: (10490-060)
Supplier: Bioss
Description: Cytidine is a nucleoside formed by a cytosine attached to a ribose ring via a beta-N1-glycosidic bond. DNA is methylated on cytidines by DNA methylases (DNMTs)to generate 5-methylcytidine (5-mC), a potent epigenetics marker and regulator of gene expression. The reverse reaction (cytidine demethylation) starts with its oxidation to hydroxymethyl- (5-hmC), formyl- (5-fC), and carboxy- (5-caC) cytidine. Several enzymes, including the Tet family of proteins have been implicated in cytidine demethylation.


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