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Catalog Number: (76634-876)
Supplier: Diagnostic Biosystems
Description: P504S has been recently described as a prostate cancer-specific gene that encodes a protein involved in the β-oxidation of branched chain fatty acids. Expression of p504S protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. P504S can be used as a positive marker for PIN.


Catalog Number: (10331-458)
Supplier: Bioss
Description: Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.


Catalog Number: (10252-930)
Supplier: Bioss
Description: DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.


Catalog Number: (TCT1165-25ML)
Supplier: TCI America
Description: CAS Number: 2622-14-2
MDL Number: MFCD00003853
Molecular Formula: C18H33P
Molecular Weight: 280.44
Form: Clear Liquid
Color: Colorless
Flash Point (°C): 42

Supplier: Adipogen
Description: Because of its relatively constant and well-known fluorescence quantum yield, quinine is also used in photochemistry as a common fluorescence standard. It has been used for imaging of oxygen evolution and oxide formation. Chloride and bromide have been shown to quench fluorescence. Generally it is famous as potassium channel blocker with antipyretic (fever-reducing), antimalarial, analgesic (painkilling), and anti-inflammatory properties.

Catalog Number: (89316-668)
Supplier: Genetex
Description: Mouse Monoclonal antibody [B016M] to sLOX-1 (Soluble form)


Catalog Number: (77440-580)
Supplier: Bioss
Description: CYP2C18 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP2C18 oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.


Catalog Number: (10407-638)
Supplier: Bioss
Description: ECHS1 (Enoyl Coenzyme A hydratase, short chain, 1) catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs, in the second step of the mitochondrial fatty acid beta-oxidation pathway.


Catalog Number: (200001-686)
Supplier: Acros Organics
Description: Size: 1L. CAS Number: 126-73-8.

SDS


Catalog Number: (10495-784)
Supplier: Bioss
Description: The Isocitrate dehydrogenase cytoplasmic enzyme is a homodimer of 416 residues that belongs to the isocitrate and isopropylmalate dehydrogenases family. IDHC catalyzes the third step of the citric acid cycle, which involves the oxidative decarboxylation of isocitrate, forming ?ketoglutarate and CO2 in a two step reaction. The first step involves the oxidation of isocitrate to the intermediate oxalosuccinate, while the second step involves the production of ?ketoglutarate. During this process, either NADH or NADPH is produced along with CO2. Ca2+ can bind to IDHC as a complex with isocitrate, acting as a competitive inhibitor of Mg2+. The IDHC enzyme is inactivated by phosphorylation at Ser-113 and contains a clasp-like domain wherein both polypeptide chains in the dimer interlock. IDHC is expressed in a wide range of species and also in organisms that lack a complete citric acid cycle.


Catalog Number: (76482-390)
Supplier: AAT BIOQUEST INC
Description: Oxidation of MitoROS™ 580 by superoxide generates red fluorescence.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Catalog Number: (76483-376)
Supplier: AAT BIOQUEST INC
Description: Zinquin is a zinc-sensitive, cell-impermeable fluorescent probe.

Small Business Enterprise Minority or Woman-Owned Business Enterprise


Catalog Number: (TCE0316-025ML)
Supplier: TCI America
Description: CAS Number: 7320-37-8 MDL Number: MFCD00005151 Molecular Formula: C16H32O Molecular Weight: 240.43 Purity/Analysis Method: <gt/>80.0% (GC) Form: Crystal Boiling point (°C): 180 Melting point (°C): 22 Flash Point (°C): 93

Catalog Number: (10349-636)
Supplier: Bioss
Description: Responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It is involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants.


Catalog Number: (10232-452)
Supplier: Bioss
Description: Produces nitric oxide (NO) which is implicated in vascular smooth muscle relaxation through a cGMP-mediated signal transduction pathway. NO mediates vascular endothelial growth factor (VEGF)-induced angiogenesis in coronary vessels and promotes blood clotting through the activation of platelets. Isoform eNOS13C: Lacks eNOS activity, dominant-negative form that may down-regulate eNOS activity by forming heterodimers with isoform 1.


Catalog Number: (10332-952)
Supplier: Bioss
Description: UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation from ATP synthesis. As a result, energy is dissipated in the form of heat (By similarity).


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