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Description: CYP2J2(Cytochrome P450 2J2) belongs to the cytochrome P450 family. This enzyme metabolizes arachidonic acid predominantly via a NADPH-dependent olefin epoxidation to all four regioisomeric cis-epoxyeicosatrienoic acids. The human CYP2J member, CYP2J2, is shown to be expressed in several tissues such as the small intestine, liver, heart, kidney, and lung and may play a role in the oxidative bioactivation of arachidonic acid.
Catalog Number: 10085-526
Supplier: Proteintech


Description: Reference compound for the fluorescent (nitric oxide) NO probe DAR-4M.
Catalog Number: 102989-680
Supplier: Adipogen


Description: Cresol, CP is an organic compound also known as hydroxytoluene, a methylphenol. It can be a solid or liquid and slowly oxidized by exposure to air. Cresols are precursors or synthetic intermediates to other compounds and materials, including plastics, pharmaceuticals, and dyes. CP or Chemically Pure grade products supplied by Spectrum are indicative of a grade suitable for general industrial use. These materials may or may not have a Certificate of Analysis available.
Catalog Number: 700003-218
Supplier: Spectrum Chemicals

Description: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity).
Catalog Number: 10401-328
Supplier: Bioss


Description: Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity).
Catalog Number: 10401-320
Supplier: Bioss


Description: The globular subunit of adipocyte complement-related protein of 30 kDa (ACRP-30) is a naturally occurring cleavage product of adiponectin, a protein made exclusively by adipocytes. ACRP-30 is an abundant serum protein and plays an important role in hyperglycemia, insulin resistance, and fatty acid oxidation. ACRP-30 signals through adiponectin receptor 1 (AdipoR1) and adiponectin receptor 2 (AdipoR2).
Catalog Number: 10821-988
Supplier: Shenandoah Biotechnology


Description: Catalyst, corrosion inhibitor, in textile printing
Catalog Number: AA11565-30
Supplier: Thermo Scientific Chemicals

Description: Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.
Catalog Number: 76101-150
Supplier: Bioss


Description: Adenosine-3',5'-cyclic monophosphate sodium salt 95%
Catalog Number: 76694-782
Supplier: AMBEED, INC


Description: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
Catalog Number: 10426-254
Supplier: Bioss


Description: Pyridone metabolite. Nitric oxide synthase (NOS) inhibitor, showing selectivity for eNOS (NOS III) versus nNOS (NOS I). Thaxtomine biosynthesis inhibitor. Mitochondrial electron transport chain inhibitor.
Catalog Number: 102513-682
Supplier: Adipogen

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Description: Nox4 is a renal gp91-phox homolog highly expressed at the site of erythropoietin production in the proximal convoluted tubule epithelial cells of the renal cortex. Nox4 is also expressed in fetal tissues, placenta, glioblastoma and vascular cells. Like gp91-phox, the enzymatic activity of Nox4 produces superoxide anions. In vascular cells, the addition of angiotensin II increases Nox4 expression, which suggests a role for Nox-4 in vascular oxidative stress response.
Catalog Number: 10404-398
Supplier: Bioss


Description: A universal, ultra pure water for your most sensitive research applications.
Catalog Number: 75832-010
Supplier: GLOBAL LIFE SCIENCES SOLUTIONS

Description: Sestrins form a small family of redox enzymes which regulate accumulation of Reactive Oxygen Species. They protect cells and their DNA against oxidative damage and regulate cell growth and viability. These genes are often deregulated in cancers and their inactivation accelerates the growth of model tumors in mice.
Catalog Number: 76011-942
Supplier: Prosci


Description: Mammalian PNK catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. It plays an important function in DNA repair following ionizing radiation or oxidative damage.PNK has been reported to participate in the repair of DNA-double strand breaks via PARP-1-dependent nonhomologous end-joining.
Catalog Number: 10375-030
Supplier: Bioss


Description: DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.
Catalog Number: 10252-918
Supplier: Bioss


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