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Catalog Number: (10252-938)
Supplier: Bioss
Description: DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.


Catalog Number: (10252-934)
Supplier: Bioss
Description: DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.


Catalog Number: (80056-262)
Supplier: MilliporeSigma
Description: A highly sensitive and specific fluorescent indicator for the direct detection of nitric oxide (NO) in vitro

Supplier: AMBEED, INC
Description: Ricobendazole 97%

Catalog Number: (10335-454)
Supplier: Bioss
Description: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria (By similarity).


Catalog Number: (89407-034)
Supplier: Hardy Diagnostics
Description: CulGenex™ Ultra Pure, molecular grade water is suitable for use in molecular biology applications that require water free of DNAses, RNAses, and proteases.

Supplier: MilliporeSigma
Description: Native xanthine oxidase from buttermilk
Supplier: Thermo Scientific Chemicals
Description: Silver plating, photography, manufacturing of other silver compounds, mirrors, as an analytical lab reagent, in coloring porcelain
Catalog Number: (80051-960)
Supplier: MilliporeSigma
Description: Guanosine 3'',5''-cyclic Monophosphate, Sodium. (cyclic GMP; G-3,5-MP; cGMP, sodium). White solid. Important intracellular messenger implicated in the action of nitric oxide in many cell types. Activates protein kinase G.

Supplier: Bachem Americas
Description: Adrenomedullin (ADM) elicits a potent and longlasting hypotensive effect and is considered as a hormone involved in blood pressure control. Additionally, ADM acts as a protective factor of blood vessels. Adrenomedullin is a potent stimulator of osteoblastic activity. Further biological activities of hADM include reduction of oxidative stress and inhibition of endothelial cell apoptosis.

Catalog Number: (10105-276)
Supplier: Prosci
Description: COLEC12 encodes a member of the C-lectin family, proteins that possess collagen-like sequences and carbohydrate recognition domains. This protein is a scavenger receptor, a cell surface glycoprotein that can bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. In addition, these receptors can recognize oxidized phospholipids so they may also participate in removing oxidatively damaged or apoptotic cells.


Catalog Number: (89029-280)
Supplier: Chemglass
Description: Stocked in brown 75 durometer. They are suitable for acids, aliphatic hydrocarbons, oxidizing agents and all petroleum products. Viton* has a low compression set and high temperature resistance. Useful temperature range of -30 to 200º C

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Catalog Number: (15425-032)
Supplier: Propper
Description: Duo-Spore® biological indicator test for weekly or daily sterilizer monitoring and for load monitoring during sterilization.


Supplier: THERMO FISHER SCIENTIFIC CHEMICALS
Description: Potassium molybdate(VI) 95%

Catalog Number: (80016-622)
Supplier: MilliporeSigma
Description: An antihyperglycemic agent that lowers blood glucose levels without stimulating insulin secretion, promoting weight gain or causing hypoglycemia. Reported to stimulate AMP-activated protein kinase (AMPK) leading to the reduction in acetyl-CoA carboxylase (ACC) activity and induction of fatty acid oxidation.

Catalog Number: (10389-234)
Supplier: Bioss
Description: Bifunctional enzyme. The C-terminal domain has epoxide hydrolase activity and acts on epoxides (alkene oxides, oxiranes) and arene oxides. Plays a role in xenobiotic metabolism by degrading potentially toxic epoxides. Also determines steady-state levels of physiological mediators. The N-terminal domain has lipid phosphatase activity, with the highest activity towards threo-9,10-phosphonooxy-hydroxy-octadecanoic acid, followed by erythro-9,10-phosphonooxy-hydroxy-octadecanoic acid, 12-phosphonooxy-octadec-9Z-enoic acid, 12-phosphonooxy-octadec-9E-enoic acid, and p-nitrophenyl phospate.


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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The original product is no longer available. The replacement shown is available.
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