You Searched For: Aluminium+oxide

Supplier: Teknova

Description: Reagent Grade Water meets the standard for ASTM TYPE with a resistance of 18 megaohms then purified by glass distillation, ion exchange, a charged carbon adsorption column and undergoes reverse osmosis, UV treatment and sterile-filtration with 0.1 micron filter.

Catalog Number: (89147-412)

Supplier: Enzo Life Sciences

Description: Very selective and potent neuronal nitric oxide synthase (nNOS/NOS I) inhibitor.

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Supplier: MilliporeSigma

Description: Inhibitor of calpain I (Ki=190nM), calpain II (Ki=220nM), cathepsin B (Ki=150nM) and cathepsin L (Ki=0.5nM). Inhibits neutral cysteine proteases and the proteasome (Ki=6µM). Protects against neuronal damage caused by hypoxia and ischemia. Inhibits apoptosis in thymocytes and metamyelocytes. Also inhibits retrovirus-induced apoptosis in L929 cells. Inhibits the proteolysis of I[kappa]B-[alpha] and I[kappa]B-[beta] by the ubiquitin-proteasome complex. Inhibits cell cycle progression at G1/S and metaphase/anaphase in CHO cells by inhibiting cyclin B degradation. Also prevents nitric oxide production by activated macrophages by interfering with transcription of the inducible nitric oxide synthase gene.

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Catalog Number: (10795-508)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to iNOS (nitric oxide synthase 2, inducible)

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Supplier: Enzo Life Sciences

Description: Nuclear factor erythroid 2-related factor 2 (Nrf2) is a transcription factor, which regulates the expression of many detoxification and antioxidant enzymes. Nrf2 can potentially play a significant role in adaptive responses to oxidative stress. Nrf2 belongs to the Cap N Collar subfamily of basic leucine zipper (CNC-bZIP) transcription factors. The NF-E2 related family comprises of Nrf1 (TCFII), Nrf2, and Nrf3 and these proteins heterodimerize with Maf proteins to bind to Maf recognition element (MARE). Under normal conditions, Nrf2 is inactive and localized in the cytoplasm through its association with Keap1. When cells are exposed to electrophiles or oxidative stress generating agents cytoplasm localization of Nrf2 is inactivated and Nrf2 translocates into the nucleus and binds to specific DNA sequence elements known as NF-E2 binding site, Maf recognition element (MARE), stress response element or anti-oxidant response element (ARE). Studies have investigated the role of Nrf2 in urinary bladder carcinogenesis, pulmonary fibrosis, and smoke-induced emphysema. A study reported Nrf2-mediated ARE transcription to be a likely target of preventative therapy in neurodegenerative disorders such as Huntington's disease.

Supplier: Thermo Scientific Chemicals

Description: 99.9% (metals basis).-200 Mesh Powder,WARNING: Irritates eyes, lungs, may be harmful if swallowed,50g,250g.

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Catalog Number: (89359-896)

Supplier: Genetex

Description: Mammalian apurinic/apyrimidinic endonuclease (APE/ref-1) is a multifunctional, bipartite enzyme that plays an important role in numerous, cellular functions. APE is responsible for repairing abasic sites in DNA and in regulating the redox state of other proteins that play roles in oxidative signaling, transcription factor regulation (Fos, Jun, NFkB, Myb, HIF1 alpha, CREB, Pax), cell cycle control (p53), and apoptosis. Altered levels of APE have also been found in some cancers. The most common form of DNA damage is the creation of abasic sites which are brought about through spontaneous loss or oxidative DNA damage, through chemically initiated hydrolysis (chemotherapy), ionizing radiation, UV irradiation, oxidizing agents, and removal of modified bases by DNA glycosylases.

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Catalog Number: (10793-466)

Supplier: Genetex

Description: Rabbit Polyclonal antibody to eNOS (nitric oxide synthase 3 (endothelial cell))

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Catalog Number: (AA33261-P2)

Supplier: Thermo Scientific Chemicals

Description: MDL: MFCD00011349

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Catalog Number: (10280-234)

Supplier: Bioss

Description: Aldehyde dehydrogenases (ALDHs) mediate the NADP+-dependent oxidation of aldehydes into acids and play an important role in the detoxification of alcohol-derived acetaldehyde, as well as in lipid peroxidation and in the metabolism of corticosteroids, biogenic amines and neurotransmitters. ALDH9A1 (aldehyde dehydrogenase family 9 member A1), also known as E3, ALDH4, ALDH7, ALDH9 or TMABADH, is a 494 amino acid cytoplasmic protein that is highly expressed in adult liver, skeletal muscle, kidney and embryonic brain. ALDH9A1 converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine and catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in a NAD-dependent reaction.

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Supplier: GROWCELLS

Description: Water for CO₂ Incubators is double distilled, 0.1um filter sterilized, has a pH of 7-9 with a conductivity of 1-20 microSiemens (Resistivity of 50K-1 M ohm) and is terminal sterilized. The water is free of all contaminants and exceeds the specifications set by CO₂ Incubator manufacturers.
Reusable & Re-autoclavable Polycarbonate Container.

Catalog Number: (80053-226)

Supplier: MilliporeSigma

Description: Cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Protects endothelial cells in a dose-dependent manner (EC50~40 µM) against paraquat (2 mM). Inhibits the oxidation of Dihydrorhodamine 123 by peroxynitrite, but does not scavenge nitric oxide (NO).

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Supplier: TLC PHARMACEUTICAL STANDARD LTD

Description: Pharmaceutical Standards, Loperamide EP Impurity G HCl (cis-Loperamide N-Oxide HCl)

Catalog Number: (10401-932)

Supplier: Bioss

Description: Receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis. Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis. In addition to binding oxLDL, it acts as a receptor for the HSP70 protein involved in antigen cross-presentation to naive T-cells in dendritic cells, thereby participating in cell-mediated antigen cross-presentation. Also involved in inflammatory process, by acting as a leukocyte-adhesion molecule at the vascular interface in endotoxin-induced inflammation. Also acts as a receptor for advanced glycation end (AGE) products, activated platelets, monocytes, apoptotic cells and both Gram-negative and Gram-positive bacteria.

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Supplier: TLC PHARMACEUTICAL STANDARD LTD

Description: Pharmaceutical Standards, Ketotifen EP Impurity D (Ketotifen N-Oxide)

Supplier: Thermo Scientific Chemicals

Description: MDL: MFCD00053997

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