You Searched For: brady b494

Description: Removal of any preexisting structures in lyophilized stocks of Aβ-peptide is the critical initial step for controlled aggregation studies. HFIP has been shown to break down β-sheet structure, disrupt hydrophobic forces in aggregated amyloid preparations, and promotes α-helical secondary structure. HFIP treatment of lyophilized Aβ-peptide resulted in a dense, homogeneous preparation of unaggregated peptide and samples can be stored as peptide films. HFIP treated Aβ-peptide samples can be stored as peptide films and can be used in controlled aggregation studies.
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
Molecular Weight: 4514.1
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Catalog Number: 103007-852

Supplier: Anaspec Inc

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Description: Enkephalins are pentapeptides involved in regulating nociception in the body. There are two enkephalin forms, one containing leucine and the other containing methionine ("met"). Both are products of the proenkephalin gene.
Sequence:YGGFM
MW:573.8 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: 102996-550

Supplier: Anaspec Inc

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Description: This is a hexapeptide with 6 histidines primarily used in tagging proteins. His tags have been used in affinity purification of recombinant proteins and have also been used in studying protein transduction in cells with the use of cell-penetrating proteins/peptides.
Sequence:HHHHHH
MW:841.9 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: 103003-718

Supplier: Anaspec Inc

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Description: Compared to the 5-isomer, tetramethylrhodamine-6-maleimide is preferably used for thiol modifications of nucleotides and nucleic acids.

Catalog Number: 103011-010

Supplier: Anaspec Inc

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Description: Tetramethylrhodamine-5-(and-6) C2 maleimide is a good alternative to tetramethylrhodamine-5-(and-6)-maleimide with excitation/emission wavelength at 544/572 nm. Its spectral characteristics are very close to those of tetramethylrhodamine-5-(and-6)-maleimide (+2 nm). It is 40% less expensive compared to tetramethylrhodamine-5-(and-6)-maleimide, and can be used for thiol modification of proteins, antibodies and peptides.

Catalog Number: 103011-002

Supplier: Anaspec Inc

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Description: Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components

Catalog Number: 103010-424

Supplier: Anaspec Inc

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Description: The SensoLyte® Rh110 Elastase Assay Kit detects elastase activity using a fluorogenic peptide substrate. Upon elastase cleavage, the peptide releases the Rh110 fluorophore with bright green fluorescence that can be detected at Ex/Em=496 /520 nm. The increase in fluorescence intensity is directly proportional to enzyme activity. The kit does not require any separation steps and can be used to continuously measure the kinetics of elastase. The longer-wavelength spectra and higher extinction coefficient of the Rh110 provide greater sensitivity and less interference from screening compounds.

Catalog Number: 103010-568

Supplier: Anaspec Inc

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Description: Dyrktide is designed as the optimal substrate sequence efficiently phosphorylated by DYRK1A, which is a dual-specificity protein kinase that is thought to be involved in brain development.
Sequence:RRRFRPASPLRGPPK
MW:1791.2 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: 103007-484

Supplier: Anaspec Inc

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Description: A cell-permeable synthetic peptide NEMO-binding domain peptide (NBD peptide) corresponding to the NEMO amino-terminal alpha-helical region is shown to block TNF-alpha-induced NF-kB activation. The interaction of IKgammaNEMO with the IKK complex is critical for the activation of the IKK complex and the subsequent activation of NF-kB.
Sequence:DRQIKIWFQNRRMKWKKTALDWSWLQTE
MW:3693.3 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: 103006-380

Supplier: Anaspec Inc

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Description: This peptide, a nuclear localization signal (NLS) peptide, is derived from the Large T antigen residues 47 to 56 (PKKKRKVEDP). It can be used to tag DNA. DNA tagged to this peptide efficiently translocates into the cell nucleus.
Sequence:PKKKRKVEDPYC
MW:1490.8 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: 103007-728

Supplier: Anaspec Inc

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Description: This sequence is the hallmark of MUC1 mucin. MUC1 is a highly glycosylated type I transmembrane glycoprotein with a unique extracellular domain consisting of a variable number of tandem repeats (VNTR) of this 20 amino acid peptide It is overexpressed on the cell surface of many human adenocarcinomas and hematological malignancies, including multiple myeloma and B-cell lymphoma, making MUC1 broadly applicable target for immunotherapeutic strategies
Sequence:PDTRPAPGSTAPPAHGVTSA
MW:1887 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: 103006-500

Supplier: Anaspec Inc

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Description: This is a Histone 3 lysine 36 dimethylated peptide. This peptide has been shown to recruit histone deacetylase complex with nucleosomes and repress transcription. In addition, owing to its epigenetic repressive mark, it allows demethylation by a Jumonji C-domain family member, JMJD5 that functions as a transcription activator by inhibiting HDAC, and regulates cell cycle proliferation.
Sequence:ATKAARKSAPATGGV-K(Me2)-KPHRYRPG-GK(Biotin)
MW:2945.5 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: 103008-168

Supplier: Anaspec Inc

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Description: Big Gastrin is also referred to as Gastrin-34. Secretion of gastrin is induced by food intake and causes the release of gastric acid in the stomach. Secreted by the G cells in the gastric mucosa, it is one of the major bioactive forms of gastrin found in tissue and plasma (the other bioactive form is gastrin-17 or little gastrin - Cat# AS-20750). Both gastrin-17 and gastrin-34 are carboxy-amidated and partially tyrosine sulfated. Binding of gastrin to the CCK2/gastrin receptor requires carboxy-amidation, however sulfation is not necessary for binding to the receptor. Binding of Gastrin to the CCK2/gastrin receptors on parietal cells of the stomach causes them to secrete hydrochloric acid (HCl) and stimulates lectin-like protein Reg expression via activation of PKC and RhoA. Gastrin also plays a role in release of Histamine and Pepsinogen.
Sequence: Pyr-LGPQGPPHLVADPSKKQGPWLEEEEEAYGWMDF-NH2
MW: 3849.3 Da
% Peak area by HPLC: 95
Storage condition: -20° C

Catalog Number: 102996-108

Supplier: Anaspec Inc

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Description: This is amino acids 73 to 92 fragment of bone morphogenetic protein (BMP) knuckle epitope. It is a member of transforming growth factor beta (TGF-B). This peptide fragment is able to raise alkaline phosphate activity in murine multipotent mesenchymal cell
Sequence:KIPKASSVPTELSAISTLYL
MW:2118.5 Da
% peak area by HPLC:95
Storage condition:-20° C

Catalog Number: 103008-450

Supplier: Anaspec Inc

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Description: HiLyte™ Fluor 555 acid, SE is an excellent amine-reactive fluorescent labeling dye that generates the protein conjugates that are only slightly red-shifted compared to those of Cy™ 3 dyes, resulting in an optimal match to filters designed for CyTM dyes.

Catalog Number: 103010-350

Supplier: Anaspec Inc

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Description: Human calcitonin reduces blood calcium, opposing the effects of parathyroid hormone (PTH). It stimulates cyclic nucleotide accumulation in human kidney cortex and medulla. Calcitonin maybe involved in osteoporosis and in Paget's disease.
Sequence: CGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP-NH2 (Disulfide bridge: 1-7)
MW: 3417.9 Da
% Peak area by HPLC: 95
Storage condition: -20° C

Catalog Number: 102998-450

Supplier: Anaspec Inc

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