You Searched For: Antibodies

Catalog Number: (RL601-4104)

Supplier: Rockland Immunochemical

Description: Secondary Rabbit Anti-IgG F(ab')2 Reacts with Cow (Bovine, Cattle)

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Supplier: Enzo Life Sciences

Description: Glutamic acid decarboxylase (GAD; E.C. 4.1.1.15) is the enzyme responsible for the conversion of glutamic acid to γ-aminobutyric acid (GABA) - the major inhibitory transmitter in higher brain regions. Two molecular forms of GAD (GAD65 and GAD67) are known from rat, cat, pig and man, and both forms are expressed in the CNS and in pancreatic islet endocrine cells. A recent Western blotting study has identified that the isoforms are regionally distributed in the brains of rats and mice. In rat pancreas, GAD65 and GAD67 appear to be differentially localised, GAD65 primarily in insulin-containing (β) cells and GAD67 in glucagon-containing (A) cells. Evidence from knock-out mice suggests that GABA generated by pancreatic GAD isoforms is not critically involved in normal islet cell development and morphology. However, β-cell-specific GAD expression has been shown to be required for the development of autoimmune diabetes in non-obese diabetic (NOD) mice.

Catalog Number: (RL713-403-002)

Supplier: Rockland Immunochemical

Description: F(Ab)2 Anti-Sheep Igg [Handl] (Rabbit) Antibody Peroxidase Conjugated - 713-403-002 F(Ab)2 Sheep Igg (Handl) Antibody Peroxidase Conjugated 500Ug

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Catalog Number: (10802-664)

Supplier: Rockland Immunochemical

Description: F(ab')2 Chicken IgG (H&L), Polyclonal antibody, Host: Rabbit, Target Species: Chicken, Format: IgG F(ab')2, Immunogen: Chicken IgG whole molecule, Applications: immunomicroscopy and flow cytometry or FACS analysis, Size: 20mg

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Catalog Number: (89141-360)

Supplier: Enzo Life Sciences

Description: IRAK (IL-1 associated serine/threonine kinase) is a critical regulator of IL-1 induced activation of the NF-κB pathway. IL-1 stimulates the association of IRAK with the heterodimer of IL-IRI and IL-IRAcP via the adapter protein MyD88. In addition to its role in IL-1 signaling, IRAK is a component of the signal transduction pathway through which TNF-R1 activates NF-κB dependent gene expression.

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Supplier: Tonbo Biosciences

Description: The 37.51 antibody reacts with mouse CD28, a 45 kDa glycoprotein which acts as a co-stimulatory receptor in support of the T cell receptor (TCR). CD28 exists as a homodimer with specificity for two known ligands, known as B7-1 (CD80) and B7-2 (CD86), expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. Other members of the CD28 family of co-stimulatory receptors include CTLA-4 (CD152), PD-1 (CD279), ICOS and BTLA.

Catalog Number: (10149-296)

Supplier: Immunoreagents

Description: The ImmunoReagents' DyLight® 594 conjugates generate red fluorescence and shows wide excitation wavelength separation from green fluorophores for multi-color applications with reduced bleedthrough. The physical characteristics of DyLight® 594 are comparable to other 594 dyes. DyLight® 594 is available for use in fluorescence microscopy, flow cytometry, Western blotting, ELISA, high-content screening and other array platforms. Excitation/Emission = 593nm / 618nm Emission Color = Red (Similar Dyes: Alexa Fluor 594, Texas Red)

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Catalog Number: (RL601-1204)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-IgG F(ab')2 Reacts with Cow (Bovine, Cattle)

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Catalog Number: (75931-570)

Supplier: Rockland Immunochemical

Description: The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. RHBDD1 is highly expressed in the testis and is involved in the cleavage of BIK, a proapoptotic member of the Bcl-2 family. Overexpression or suppression by RNAi of RHBDD1 in 293 cells will reduce or enhance BIK-mediated apoptosis, respectively, demonstrating that RHBDD1 modulates BIK-mediated apoptotic activity. In GC-1 cells, a spermatogonia cell line that can differentiate into spermatids within the seminiferous tubules, suppression of RHBDD1 expression by RNAi caused the cells to lose the ability to survive and differentiate in mouse seminiferous tubules, suggesting that RHBDD1 may be associated with mammalian spermatogenesis.

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Catalog Number: (75933-764)

Supplier: Rockland Immunochemical

Description: ZNF346, also known as JAZ (just another zinc-finger protein), is a nucleolar, zinc finger protein which preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids with high affinity via C2H2 zinc fingers. ZNF346 contains four CH-type zinc finger motifs that are connected by long (28-38) amino acid linker sequences. ZNF346 is expressed in all tissues tested and localizes to the nucleus, primarily the nucleolus. ZNF346 is exported by exportin-5 but translocates back into nuclei by a facilitated diffusion mechanism. ZNF346 interacts with ILF3 in an RNA-independent manner and may be involved in cell growth and survival.

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Catalog Number: (RL200-301-E40)

Supplier: Rockland Immunochemical

Description: Anti-Syntaxin antibody is suitable for use in Western Blotting and IHC. Expect a band or approximately 36 kDa in size corresponding to syntaxin Proteins in Western blot of Rat brain lysate.

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Catalog Number: (RL610-1202)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-IgG (H&L) Reacts with Mouse

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Catalog Number: (10141-214)

Supplier: Tonbo Biosciences

Description: The HRPN immunoglobulin is useful as an isotype-matched control. The HRPN immunolglobulin has an unknown binding specificity and is used as an isotype control for rat IgG1 antibodies.

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Catalog Number: (RL601-4304)

Supplier: Rockland Immunochemical

Description: This product has been assayed against 1.0 µg of Bovine IgG in a standard capture ELISA using ABTS (2,2’-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid])

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Supplier: Tonbo Biosciences

Description: The N418 antibody reacts with mouse CD11c, also known as integrin alpha X. This 150 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha X (CD11c) assembles with Integrin beta-2 (CD18) into a receptor complex known as CR4 which can bind and induce signaling through ICAMs and VCAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

Catalog Number: (10150-762)

Supplier: Immunoreagents

Description: TRITC (Tetramethylrhodamine isothiocyanate) is a popular rhodamine derivative pink in color but emits a red-orange color upon Emission at 580nm. TRITC is frequently paired with FITC in double labeling experiments and conjugated antibodies are often used in immunofluorescence microscopy, flow cytometry, FLISA (fluorescent ELISA) and high throughput screening assays. These conjugates are best excited with the 532 nm spectral line of the He-Ne laser and are also recommended as a second color detection reagent in in situ hybridization applications. (Excitation/Emission = 555nm / 580nm Emission Color = Orange to Red (Similar Dyes: Alexa Fluor 555, Cy3, DyLight 550)

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