You Searched For: Antibodies

Catalog Number: (RL200-301-F93)

Supplier: Rockland Immunochemical

Description: Anti-Kv1.3 Antibody is suitable for use in WB, IP, and IHC. Expect a band approximately ~70kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

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Catalog Number: (89146-246)

Supplier: Enzo Life Sciences

Description: VASP (vasodilator stimulated phosphoprotein) is a proline-rich protein substrate of cAMP- and cGMP-dependent protein kinases. Phosphorylation of VASP at Ser-157 causes a mobility shift in SDS gel electrophoresis from 46 to 50 kDa, which has been used as a convenient marker to monitor cyclic nucleotide-dependent protein kinase activity. VASP is the founding member of the Ena-VASP protein family, comprising the Drosophila protein Enabled (Ena), its mouse homologue Mena (mammalian Enabled), and mouse EVL (Ena-VASP-like protein). With these proteins VASP shares a conserved overall domain organization:
a) the conserved N-terminal Ena-VASP homology domain 1 (EVH1), which mediates binding to a proline-rich motif
b) a more divergent proline-rich central domain (which is responsible for profilin binding)
c) a conserved C-terminal EVH2 domain.

VASP is expressed in a variety of mammalian cell types and tissues. In cultured cells, VASP is associated with focal adhesions, cell-cell contacts, microfilaments, and highly dynamic membrane regions. From in vitro binding data VASP has been suggested to link profilin to zyxin, vinculin, and the Listeria spp. surface protein ActA, respectively. Functional evidence indicates that VASP is a crucial factor involved in the enhancement of actin filament formation and the actin-dependent motility of intracellular bacterial pathogens.

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Catalog Number: (10802-566)

Supplier: Rockland Immunochemical

Description: The esophageal cancer-susceptibility gene 2 (ECRG2), also known as SPINK7, is a novel tumor suppressor gene identified from the human esophagus. It interacts directly with metallothionein 2A and urokinase-type plasminogen activator (uPA), and downregulates the activity of uPA, leading to reduced cancer cell migration, invasion and metastasis. ECRG2 forms a complex with uPA and its receptor uPAR, modifying the dynamic association of uPAR with beta1 integrins and disrupting the Src/MAP kinase pathway that normally stimulates cell migration and invasion. ECRG2 may thus represent a novel therapeutic target for cancer.

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Catalog Number: (RL612-443-026)

Supplier: Rockland Immunochemical

Description: (Min X Human Serum Proteins)is designed for immunofluorescence microscopy, fluorescence based plate assays (FLISA) and fluorescent western blotting.100ug

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Catalog Number: (RL210-406-B68)

Supplier: Rockland Immunochemical

Description: This Protein-A purified, MBP-cross-adsorbed antibody is suitable for ELISA and western blotting of mouse and human NAG-1 Protein.  For detection of NAG-1 in mouse serum, a sandwich ELISA is suggested using this antibody in combination with anti-NAG-1/GDF1.

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Catalog Number: (RL612-401-E42)

Supplier: Rockland Immunochemical

Description: Anti-Tau pS416 (Rabbit) antibody is suitable for use in Western Blotting. Expect bands or approximately 59, 65, 68 kDa in size corresponding to tau Proteins phosphorylated at Ser416 in the appropriate cell lysate or extract.

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Catalog Number: (RL210-301-C55)

Supplier: Rockland Immunochemical

Description: Anti-Mouse Ebi-3 (Mouse) Monoclonal Antibody - 210-301-C55 Ebi-3 Antibody 100Ug

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Catalog Number: (76234-902)

Supplier: Rockland Immunochemical

Description: Rockland produces a wide range of human GST antibodies in our laboratories. Select appropriate GST antibodies for your research by isotype, epitope, applications and species reactivity. There are 22 members of the human GST family of proteins. GST is responsible for the conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. The amino acid sequence GST is highly conserved in most organisms including mammals. GSTs proteins are typically homodimeric, with both heterologous GST dimers have been observed. GST monomers have an average molecular weight of approximately 25-28 kDa in size. Note a different form of non-human GST (Glutathione-S-Transferase) is used as a protein expression tag commonly in molecular biology applications. All anti-GST antibodies my not react with recombinant GST-fusion proteins.

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Catalog Number: (RL612-401-C82)

Supplier: Rockland Immunochemical

Description: Anti-GluR1 pS831 (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 100 kDa in size corresponding to the GluR1 Protein phosphorylated at Ser 831.

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Catalog Number: (RL600-401-671)

Supplier: Rockland Immunochemical

Description: This affinity purified antibody has been tested for use in ELISA, immunochemistry and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 69 kDa in size corresponding to FANCG by western blotting.

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Catalog Number: (RL200301H87)

Supplier: Rockland Immunochemical

Description: Anti-Ikkgamma Antibody Detects Human Ikkgamma. Nf-Kappab (Nuclear Factor Kb) Is Sequestered In The Cytoplasm By Ikb Family Of Inhibitory Proteins That Mask The Nuclear Localization Signal Of Nf-Kappab Thereby Preventing Translocation Of To The Nucleus.

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Catalog Number: (76284-758)

Supplier: Enzo Life Sciences

Description: Recombinant monclonal antibody (Mouse IgG1κ).

Recommended Applications: Flow Cytometry, IF, IHC (PS), IP, WB

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Catalog Number: (10800-128)

Supplier: Rockland Immunochemical

Description: Ataxin-1 is a member of the ATXN1 protein family and contains a single AXH domain. It is a neurodegenerative disorder protein thought to have a role in the metabolism of RNA as it has been shown to localize to the RNA and transcription dependent inclusions within the nucleus. A mutation of Ataxin-1 is the cause of spinocerebellar ataxia type-1 (SCA1), a progressive, neurodegenerative disease that is autosomal dominant and primarily affects the Purjinke cells found in brain stem neuronal populations and the cerebellum. Expression of Ataxin-1 is almost ubiquitous, except in the brain where it is isolated to populations of neurons.

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Catalog Number: (200062-116)

Supplier: Enzo Life Sciences

Description: Protein Kinase C (PKC) is a large superfamily of serine/threonine kinases that mediate essential cellular signals required for activation, proliferation, differentiation and survival. There are at least ten PKC isotypes that are closely related in structure but that have distinct patterns of tissue distribution and function. The PKC isotypes can be subdivided into three classes based on primary structure and biochemical properties. These are: classical or conventional PKC isotypes (cPKC), novel PKC isotypes (nPKC) and atypical PKC isotypes (aPKC).

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Catalog Number: (RL610-446-002)

Supplier: Rockland Immunochemical

Description: The emission spectra for this DyLight® conjugate match the principle output wavelengths of most common fluorescence instrumentation.

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Catalog Number: (75933-804)

Supplier: Rockland Immunochemical

Description: KLF4 is a transcription factor that functions as both a transcriptional activator and repressor to regulate proliferation and differentiation of multiple cell types. The role of KLF4 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing KLF4 and the transcription factors POU5F1, Sox2, and Lin28 along with c-Myc in mouse fibroblasts. More recently, experiments have demonstrated that iPS cells could be generated using expression plasmids expressing KLF4, Sox2, POU5F1 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine. KLF4 interacts directly with POU5F1 and Sox2 in iPS and ES cells and activates the target gene NANOG.

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