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Description: The OKT3 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Catalog Number: 10051-754

Supplier: Tonbo Biosciences

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Description: MEK1 antibodies detect the MEK1 isoform. Mitogen-activated protein kinase kinase 1, also known as MKK or MEK, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. The MEK1 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.

Catalog Number: 76262-672

Supplier: Rockland Immunochemical

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Description: Anti-Sheep Igg (Handl) (Rabbit) Antibody Biotin Conjugated (Min X Human Serum Proteins) - 6134628-0500 Sheep Igg (Handl) Antibody Biotin Conjugated Pre-Adsorbed 500Ug

Catalog Number: RL6134628-0500

Supplier: Rockland Immunochemical

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Description: Secondary Rabbit Anti-IgG (H&L) Reacts with Rat

Catalog Number: RL612-4526

Supplier: Rockland Immunochemical

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Description: Recommended Applications: Flow Cytometry

Species reactivity: Human

Catalog Number: 76002-792

Supplier: Enzo Life Sciences

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Description: Secondary Rabbit Anti-IgG (H&L) Reacts with Pig (Swine, Porcine)

Catalog Number: RL614-4002

Supplier: Rockland Immunochemical

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Description: H&L , Dylight 594 Conjugate , Highly Cross-absorbed , , ImmunoReagents Inc. ImmunoReagents# GtxMu-003-F2594NHSX

Catalog Number: 10151-564

Supplier: Immunoreagents

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Description: AHSP Antibody detects Alpha hemoglobin stabilizing protein (AHSP). AHSP acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development.

Catalog Number: RL100401E79

Supplier: Rockland Immunochemical

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Description: Anti-Mouse Igg Iga Igm (Handl) (Goat) Antibody Peroxidase Conjugated (Min X Bv, Hs, Hu Serum Proteins) - 610-103-430 Mouse Igg Iga Igm (Handl) Antibody Peroxidase Conjugated Pre-Adsorbed 1 Mg

Catalog Number: RL610-103-430

Supplier: Rockland Immunochemical

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Description: Mitofusin 1 (MFN1) and the related protein MFN2 are mitochondrial membrane GTPase proteins that play a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes (1,2). MFN1 and MFN2 form homotypic and heterotypic complexes and coordinately regulate mitochondrial fusion and are essential for embryonic development (3). When ectopically expressed, MFN1 inhibits the apoptosis-associated amino-terminal conformation change in the apoptotic protein Bax but not its mitochondrial translocation, indicating that MFN1 is involved in the regulating the activation of Bax on the outer mitochondrial membrane (4).

Catalog Number: 75933-878

Supplier: Rockland Immunochemical

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Description: CXCR4 antibody detects a G coupled -protein receptor. Human immunodeficiency virus (HIV) and related viruses require coreceptors, in addition to CD4, to infect target cells. Some G protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors. Among them, CXCR4 (fusin, LESTR or HUMSTR) is a principal coreceptor for T-cell tropic strains of HIV-1 fusion and entry of human white blood cells. CXCR4 is also required for the infection by dual-tropic strains of HIV-1 and mediates CD-4 independent infection by HIV-2. The a-chemokine SDF-1 is the ligand for CXCR4 and prevents infection by T-tropic HIV-1. CXCR4 associates with the surface CD4-gp120 complex before HIV enters target cells. CXCR4 messenger RNA levels correlated with HIV-1 permissiveness in diverse human cell types. Antibodies to CXCR4 block HIV-1 and HIV-2 fusion and infection of human target cells. The amino-terminal domain and the second extracellular loop of CXCR4 serve as HIV binding sites. Anti-CXCR4 antibodies are ideal for investigators involved in Cytokines and Growth Factors or Infectious Disease reasearch.

Catalog Number: 10801-034

Supplier: Rockland Immunochemical

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Description: ImmunoReagents’ Horseradish Peroxidase (HRP) antibody conjugates are the most popular conjugates due to their high level of sensitivity, stability, and low costs. HRP conjugates are an ideal choice for use in ELISA, Immunohistochemistry (IHC), and Western blotting experiments.

Catalog Number: 10150-974

Supplier: Immunoreagents

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Description: Fab Anti-Guinea Pig Igg (Handl) (Rabbit) Antibody Fluorescein Conjugated - 806-4202 Fab Guinea Pig Igg (Handl) Antibody Fluorescein Conjugated 500Ul

Catalog Number: RL806-4202

Supplier: Rockland Immunochemical

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Description: Intermediate filaments (IFs) are a structurally related family of cellular proteins that appear to be intimately involved with the cytoskeleton. Human keratin 18(KRT18) and the homologous mouse Endo B are type I IF protein subunits whose expression is restricted in adults to a variety of simple epithelial tissues. The KRT18 gene is 3,791 bp long and the keratin 18 protein is coded for by 7 exons. The K18 gene is 3791 bp in length and the K18 protein is coded for by seven exons. By Southern blotting using the genomic DNA PCR product, the gene for keratin 18 is assigned to chromosome 12. Mutation of human keratin 18 in association with cryptogenic cirrhosis. This antibody is suitable for researchers interested in cancer research, cardiovascular diseases, and cytoskeletal signaling research.

Catalog Number: 10801-076

Supplier: Rockland Immunochemical

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Description: ImmunoReagents’ Biotinylated antibody conjugates are widely used due to their ability to enhance antibody signal in most immunoassays. Biotinylated secondary antibodies are used in most immunoassay formats (i.e., ELISA, Immunohistochemistry (IHC), and Western blotting). While Biotinylated antibodies by themselves do not produce a signal that can be visualized, biotin has a high affinity and specificity to Streptavidin/Avidin. Using ImmunoReagents’ streptavidin conjugates with biotinylated antibodies results in signal amplification.

Catalog Number: 10149-796

Supplier: Immunoreagents

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Description: Anti-GABA(A) Receptor beta 3 pS408/pS409 (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 53 kDa in size corresponding to GABA(A) receptor beta 3.

Catalog Number: RL612-401-D51

Supplier: Rockland Immunochemical

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