You Searched For: Antibodies

Supplier: ABCAM INC.

Description: Anti-ICAM1 Rabbit Monoclonal Antibody [clone: EPR19938]

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Catalog Number: (10801-136)

Supplier: Rockland Immunochemical

Description: The exosome is involved in a multitude of cellular RNA processing and degradation events. DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species. DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain. It is widely expressed with highest expression in testis and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis.

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Catalog Number: (RL610-700-124)

Supplier: Rockland Immunochemical

Description: Secondary Donkey Anti-IgG (H&L) Reacts with Mouse

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Catalog Number: (75877-482)

Supplier: MP Biomedicals

Description: Peroxidase-conjugated goat IgG fraction to rabbit IgG (whole molecule) is the lyophilized powder of horseradish peroxidase (HRP)-conjugated goat IgG fraction to rabbit IgG (whole molecule) and buffer salts. Anti-Human IgG is developed in goat using IgG from pooled normal human serum as the immunogen. Whole antiserum is fractionated and then further purified by ion exchange chromatography to provide the IgG fraction of antiserum. This fraction is essentially free of other goat serum proteins.

Specificity for human IgG is determined by immunoelectrophoresis (IEP) versus purified human IgA, IgG, IgM, Bence Jones kappa, and Bence Jones lambda myeloma proteins. Identity and purity of the antibody is established by immunoelectrophoresis (IEP), prior to conjugation. Electrophoresis of the antibody preparation followed by diffusion versus anti-goat IgG and anti-goat whole serum result in single arcs of precipitation in the gamma region.

Peroxidase-conjugated goat IgG fraction to rabbit IgG (whole molecule) product is suitable for use as a reagent in enzyme immunoassays (EIA), cell and tissue staining (for light microscopy), cell and tissue labeling (for electron microscopy), and blot immunostaining. Note: F(ab')2 fragments are recommended for staining of cells or tissues which contain Fc receptors. Affinity purified antibodies or their fragments are recommended to avoid non-specific binding from inherent antibodies of host animals.

Antibody and highly purified HRP (Rz>3.0) are conjugated under defined conditions to obtain optimally labeled product. Conjugated protein is purified by salt fractionation. The product is dialyzed into 0.02M sodium phosphate, 0.14M sodium chloride, pH 7.3, adjusted to standard titer, filtered through a 0.22 µm filter, vialed and lyophilized.

The total protein is measured using the Biuret procedure with bovine albumin as the standard. To ensure that the product titer falls within the required range, antibody titer is standardized by microtiter plate ELISA with rabbit IgG. The product is tested for purity and specificity at final concentration by immunoelectrophoresis. The antibody is predominantly goat IgG; no trace of albumin is detected.

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Catalog Number: (ABCA_AB190760-500U)

Supplier: ABCAM INC.

Description: Anti-Kappa light chain Mouse Monoclonal Antibody [clone: KLC264]

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Catalog Number: (ABCA_AB189995-50UG)

Supplier: ABCAM INC.

Description: Anti-AP-2 complex subunit alpha-1 Goat Polyclonal Antibody

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Supplier: Tonbo Biosciences

Description: The PC61.5 antibody is specific for mouse CD25, a 55 kDa surface protein also known as the Interleukin-2 Receptor alpha chain, or IL-2R alpha. CD25 may bind IL-2 by itself, although with low affinity and without induction of cell signaling. CD25 is also expressed within a high-affinity complex, along with the IL-2R beta chain (CD122) and the common gamma chain (CD132), to form a signaling receptor complex. Expression of CD25 varies during developmental stages of T and B cells, is induced on activated mature T and B cells, and is present on subsets of dendritic cells. CD25 signaling as part of the IL-2 receptor complex triggers T cell activation and proliferation, as well as modulating the differentiation and function of Th17 cells, T regulatory (Treg) cells, and dendritic cells. The PC61.5 antibody is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used to distinguish Treg cells from na�ve or conventional T cells which are CD25-. This clone has also been reported for depletion of Treg cells in vivo (use format suitable for functional assays).

Catalog Number: (RL006-0107)

Supplier: Rockland Immunochemical

Description: Produced through a multi-stage process that includes delipidation, salt fractionation, ion-exchange chromatography, gel filtration, and affinity chromatography. No contaminating proteins are observed when assayed at a protein concentration of 20mg/mL against anti-whole serum or anti-fragment specific antisera. All immunoglobulin fragments are prepared from highly purified, whole molecules subject to enzymatic digestion.

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Catalog Number: (RL600-401-936)

Supplier: Rockland Immunochemical

Description: This affinity-purified antibody has been tested for use in ELISA and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 80-95 kDa in size corresponding to MECT1 Protein by western blotting.

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Catalog Number: (ABCA_AB87122-100UG)

Supplier: ABCAM INC.

Description: Anti-Aldolase C Rabbit Polyclonal Antibody

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Catalog Number: (ABCA_AB85163-100UG)

Supplier: ABCAM INC.

Description: Anti-Endothelin A Receptor/ET-A Rabbit Polyclonal Antibody

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Catalog Number: (ABCA_AB321664-100U)

Supplier: ABCAM INC.

Description: Anti-GM130 Rabbit Monoclonal Antibody [clone: EP892Y] (Alexa Fluor® 750)

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Catalog Number: (95045-844)

Supplier: Enzo Life Sciences

Description: Stats (Signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, Stats enter the nucleus to regulate transcription of many different genes.

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Catalog Number: (ABCA_AB229542-100U)

Supplier: ABCAM INC.

Description: Anti-SEC61B Rabbit Polyclonal Antibody

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Catalog Number: (ABCA_AB90618-100UL)

Supplier: ABCAM INC.

Description: Anti-Fascin (phospho S39) Rabbit Polyclonal Antibody

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Catalog Number: (ABCA_AB96569-100UG)

Supplier: ABCAM INC.

Description: Anti-PDGFR alpha Mouse Monoclonal Antibody [clone: 16A1]

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