You Searched For: Antibodies

Catalog Number: (RL709-1918)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-F(ab')2 Reacts with Human

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Catalog Number: (75930-236)

Supplier: Rockland Immunochemical

Description: Nanos1 is one of three known mammalian homologs to the Drosophila gene nanos. Nanos1 is an RNA-binding protein containing a zinc-finger motif and is expressed in the developing nervous system and continues in the adult brain. Interestingly, unlike mice deficient in either nanos2 or nanos3, mice lacking the nanos1 gene develop normally with no sign of abnormalities. Recently it has been found that expression of nanos1 mRNA is down-regulated by E-cadherin in a human breast cancer cell line and the amino-terminal domain on Nanos1 interacts with the E-cadherin-binding protein p120ctn. Furthermore, overexpression of Nanos1 in human colorectal DLD1 cancer cells functionally abolished cell-cell adhesion, allowing the cancer cells to develop strong migratory and invasive properties. These results suggest that targeting Nanos1 might prove an effective strategy in the treatment of E-cadherin-negative tumors.

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Catalog Number: (76002-782)

Supplier: Enzo Life Sciences

Description: Recommended Applications: IHC, WB

Species reactivity: Human, Mouse, Rat

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Catalog Number: (RL610-4902)

Supplier: Rockland Immunochemical

Description: Secondary Rabbit Anti-IgG (H&L) Reacts with Mouse

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Catalog Number: (RL20043430100)

Supplier: Rockland Immunochemical

Description: Polyclonal antibody, Host:rabbit, Species reactivity:Yeast, isotype:IgG, Label:Peroxidase (Horseradish), Immunogen:Alcohol Dehydrogenase [Yeast], Application:Western Blot

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Catalog Number: (75930-016)

Supplier: Rockland Immunochemical

Description: Anti-Monkey IgG (gamma chain) antibody generated in goat detects specifically monkey IgG (gamma chain). This secondary antibody anti-Monkey is ideal for investigators who routinely perform ELISA, Sandwich ELISA, titration assays, western-blot, immunoprecipitation and more generally immunoassays.

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Catalog Number: (10801-508)

Supplier: Rockland Immunochemical

Description: Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.

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Catalog Number: (RL20043720100)

Supplier: Rockland Immunochemical

Description: Polyclonal antibody, Host:rabbit, Species reactivity:Chicken, isotype:IgG, Label:Peroxidase (Horseradish), Immunogen:Anti-Lysozyme Antibody was produced by repeated immunizations with hen egg white Lysozyme protein., Application:Western Blot

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Catalog Number: (75935-424)

Supplier: Rockland Immunochemical

Description: Syntaphilin was initially identified in a yeast two-hybrid screen with the carboxy terminal region of Syntaxin-1 as bait. Syntaxin-1 is a key component of the synaptic vesicle docking machinery that forms the SNARE complex with synaptobrevin and SNAP-25. Syntaphilin competes with SNAP-25 for binding to syntaxin-1 and inhibits the formation of the SNARE complex, thereby potentially regulating synaptic vesicle exocytosis. Syntaphilin also binds dynamin-1 and inhibits dynamin-dependent endocytosis. Mice lacking syntaphilin show an increased level of mitochondrial motility and a reduced density of axonal mitochondria. This correlates with an enhanced short-term facilitation and significant impairments in motor ability, suggesting syntaphilin plays a major role in presynaptic function. Multiple isoforms are known to exist.

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Catalog Number: (75928-770)

Supplier: Rockland Immunochemical

Description: IKAP was initially identified as a scaffold protein of the IkB kinase complex that could bind to IKKa, IKKb, NF-kB, and the NF-kB-inducing kinase (NIK), although later evidence has cast doubt on this. More recent reports show that mutations in IKAP such as a frameshift leading to a truncated protein or a missense mutation that leads to defective phosphorylation are responsible for the autosomal recessive genetic disease familial dysautonomia (FD). Reports indicating that it forms part of the RNA polymerase II transcription elongation complex suggest that this disease may be due to compromised transcription elongation. More recently, it was shown that IKAP associates with c-Jun N-terminal kinase (JNK) and could specifically enhance JNK activation induced by the upstream JNK activators MEKK1 and ASK1, indicating another possible cause for FD. At least two isoforms of IKAP are known two exist.

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Catalog Number: (75932-618)

Supplier: Rockland Immunochemical

Description: Tau is a key microtubule-associated protein that plays an important role in the formation of microtubules in axons. Six tau isoforms have been identified as products of a single gene produced by alternative mRNA splicing. Tau mutations have been implicated in many neurodegenerative disorders such as Alzheimer’s disease (AD), Pick’s disease and progressive supranuclear palsy. Tau Antibody is ideal for researchers interested in neuroscience research.

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Catalog Number: (10150-716)

Supplier: Immunoreagents

Description: ImmunoReagents’ FITC Conjugates are used in immunofluorescence microscopy, flow cytometry, FLISA (fluorescent ELISA) and high throughput screening assays. Fluorescein is typically excited by the 488 nm line of an argon laser, and emission is collected at 518 nm. FITC antibody conjugates are yellow-orange in color but emit a yellow-green color upon Em 518 nm. FITC antibody conjugates are sensitive to light. The typical FITC to antibody ratio (F/P) is >4.0 Excitation/Emission = 494nm / 518nm Emission Color = Green (Similar Dyes: Alexa Fluor 488, Cy2, DyLight ® 488)

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Catalog Number: (RL610-145-007)

Supplier: Rockland Immunochemical

Description: The emission spectra for this DyLight® conjugate match the principle output wavelengths of most common fluorescence instrumentation.

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Catalog Number: (RL603-105-007)

Supplier: Rockland Immunochemical

Description: Anti-Chicken Igm (Mu Chain) (Goat) Antibody Alkaline Phosphatase Conjugated - 603-105-007 Chicken Igm (Mu Chain) Antibody Alkaline Phosphatase Conjugated 1 Mg

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Catalog Number: (RL200106238S)

Supplier: Rockland Immunochemical

Description: Anti-Glutamine Synthetase (Microbial) (Goat) Antibody Biotin Conjugated Has Been Assayed Against 1 Ug Of Glutamine Synthetase In A Standard Capture ELISA Using Peroxidase Conjugated Streptavidin And Abts As A Substrate For 30 Minutes At Room Temperature.

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Catalog Number: (RL210-406-B54)

Supplier: Rockland Immunochemical

Description: IL-27 is expressed in activated antigen presenting cells including monocytes, endothelial cells, and dendritic cells, for example mouse CD4 splenocytes. This purified antibody has been tested for use in western blotting.

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