You Searched For: Electrophoresis Stains

Catalog Number: (89141-472)

Supplier: Enzo Life Sciences

Description: The β-amyloid peptide (β A4), proteolytically released from the amyloid precursor protein (APP), provides the principal component of senile plaques in Alzheimer's disease. Cleavage of APP by α-secretase or alternatively by β-secretase leads to generation and extracellular release of soluble APP peptides, S-APP-α and S-APP-β, respectively, and the retention of corresponding membrane-anchored C-terminal fragments, C83 and C99. Subsequent processing of C83 by γ-secretase yields P3 peptides. This is the major secretory pathway and is nonamyloidogenic. Alternatively, presenilin/ nicastrin-mediated γ-secretase processing of C99 releases the amyloid β proteins, amyloid-β 40 (Aβ40) and amyloid-β 42 (Aβ42), major components of amyloid plaques, and the cytotoxic C-terminal fragments, γ-CTF(50), γ-CTF(57) and γ-CTF(59).

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Catalog Number: (76284-986)

Supplier: Enzo Life Sciences

Description: Recombinant monclonal antibody (Mouse IgG2aκ).

Recommended Applications: Flow Cytometry, IHC (FS)

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Catalog Number: (10049-488)

Supplier: Enzo Life Sciences

Description: Alpha-crystallins, which are part of the small Heat shock family members, are major water-soluble proteins present in the lens of the mammalian eye. Phosphorylation of serine residues which occurs during development and in response to stress, is intimately linked with its function. Chaperone activity requires, and is modulated by, oligomerization and is limited to binding unfolded intermediates to prevent irreversible aggregation.

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Supplier: Rockland Immunochemical

Description: ALKALINE PHOSPHATASE antibody has been assayed against 1.0 ug of Alkaline Phosphatase [Calf Intestine] in a standard ELISA using Peroxidase conjugated Affinity Purified anti-Sheep IgG [H&L] (Goat) and (ABTS (2,2’-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid])

Catalog Number: (RL013-0050)

Supplier: Rockland Immunochemical

Description: Agarose-Protein gels can also be used to remove unwanted cross-reactive antibodies. The total bound protein is 10.0 mg/ml per vial for IgG gels and 5.0 mg per vial for F(ab')2 gels.

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Catalog Number: (89154-474)

Supplier: Enzo Life Sciences

Description: Host: Rat, Isotype: IgG2a

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Catalog Number: (75931-962)

Supplier: Rockland Immunochemical

Description: The F box protein Skp2 (S-phase kinase-associated protein 2) is oncogenic, and its frequent amplification and overexpression correlate with the grade of malignancy of certain tumors. Skp2 controls p300-p53 signaling pathways in cancer cells, making it a potential molecular target for cancer therapy. This gene positively regulates the G(1)-S transition by controlling the stability of several G(1) regulators, such as the cell cycle inhibitor p27. This study provides evidence of a role for an F-box protein in oncogenesis and establishes SKP2 as a protooncogene causally involved in the pathogenesis of lymphomas. This antibody is suitable for researchers interested in cancer research.

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Catalog Number: (RL612-401-D54)

Supplier: Rockland Immunochemical

Description: Anti-GABA(B) Receptor 1 pS923 (Rabbit) antibody is suitable for use in Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 102 kDa in size corresponding to GABA(B) receptor 1 Protein phosphorylated at Ser923.

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Catalog Number: (RL613-4502)

Supplier: Rockland Immunochemical

Description: Anti-Sheep IgG (H&L) is suitable for use in immunoelectrophoresis, western-blot, competitive western-blot, ELISA and competitive ELISA assays. Specific conditions for reactivity and signal detection should be optimized by the end user.

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Supplier: Tonbo Biosciences

Description: The UCHT2 antibody is specific for human CD5, a 67 kD transmembrane glycoprotein, that is expressed on most thymocytes, mature T cells, and a subset of B cells. CD5 is involved in modulating antigen receptor signaling in both T and B cells and binds to CD72, expressed on B cells.

Supplier: Tonbo Biosciences

Description: The HP-3G10 antibody is specific for human CD161, also known as NKR-P1A, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. CD161 exists as a homodimer which is prominently expressed on natural killer (NK) and NKT cells, where it is proposed to regulate the function of both cell types. CD161 is also found on T cell subsets, including T regulatory cells (Tregs), memory/effector CD4+ T cells, and CD8+ T cells. Th17 cells have been demonstrated to co-express CD161, as surface IL-17A+ cells are contained within the CD161+ fraction of CD4 T cells, so that CD161 (in combination with CCR6) is often used as a marker for enrichment of Th17 cells.

Catalog Number: (RL609-1603)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-IgG F(c) Reacts with Human

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Catalog Number: (75932-970)

Supplier: Rockland Immunochemical

Description: TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain and localizes to the sarcoplasmic reticulum (SR) in muscle tissues. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure; the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.

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Catalog Number: (RL712-1807)

Supplier: Rockland Immunochemical

Description: Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring extremely low background levels, absence of F(c) mediated binding, lot-to-lot consistency, high titer and specificity.

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Catalog Number: (10800-586)

Supplier: Rockland Immunochemical

Description: Cat IgG F(ab')2 Fragment

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Supplier: Enzo Life Sciences

Description: The mammalian PDI (Protein disulfide-isomerase) family encompasses several highly divergent proteins which are involved in the processing and maturation of secretory proteins in the endoplasmic reticulum by catalyzing the rearrangement of disulfide bonds.

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