You Searched For: ACS Material, LLC

Supplier: Tonbo Biosciences

Description: The OKT4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.

Catalog Number: (10049-746)

Supplier: Enzo Life Sciences

Description: Bradykinin (BK) is a nine-amino acid peptide produced by kallikrein cleavage of kininogen precursor proteins in tissue and plasma, and is an important regulator of vascular and pain responses to tissue injury. Two receptors (B1 and B2) have been identified as mediators of BK signaling, and are both seven-transmembrane domain-containing GPCRs. The B2 receptor is constitutively expressed in smooth muscle and neurons, whereas B1 expression is induced following injury. B2 receptors signal via Gq alpha subunits, leading to activation of phospholipase Cbeta, hydrolysis of PI, and an intracellular increase in free calcium, although coupling through Gi, Gs, and G12/13 has also been observed.

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Catalog Number: (89163-218)

Supplier: Enzo Life Sciences

Description: Host: Rabbit

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Catalog Number: (RL201032340100)

Supplier: Rockland Immunochemical

Description: Polyclonal antibody, Host:Goat, Species reactivity:Rhizopus, Label:Peroxidase (Horseradish), Immunogen:Glucoamylase [Rhizopus], Application:ELISA, Western Blot, ImmunoPrecipitation

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Catalog Number: (10802-064)

Supplier: Rockland Immunochemical

Description: Biotin, Polyclonal Antibody, Host: Rabbit, Format: IgG, Label: Texas Red* Conjugated, Immunogen: Biotin conjugated Keyhole Limpet Hemocyanin (KLH), Applications: IF Microscopy, Size: 20mg

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Catalog Number: (75928-928)

Supplier: Rockland Immunochemical

Description: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2. ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues. ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.

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Catalog Number: (89154-058)

Supplier: Enzo Life Sciences

Description: Host: Rat, Isotype: IgG1

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Catalog Number: (75931-688)

Supplier: Rockland Immunochemical

Description: The arginine/serine-rich coiled-coil 1 protein (RSRC1) was initially identified as a non-snRNP splicing factor that has a role in both the constitutive and alternative splicing of pre-mRNA molecules. In cellular nuclear extracts immunodepleted of RSRC1, the second step of pre-mRNA splicing is blocked; recombinant RSRC1 is able to restore splicing activity. RSRC1 has also been reported to be associated with schizophrenia as well as a unique marker of bone marrow-derived stem cells that also express the cdc34 marker.

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Catalog Number: (RL610-106-115)

Supplier: Rockland Immunochemical

Description: Anti-Mouse Igg + Igm (Handl) (Goat) Antibody Biotin Conjugated Minimum Cross Reactivity To Bovine, Horse And Human Serum Proteins - 610-106-115 Mouse Igg + Igm (Handl) Antibody Biotin Conjugated Pre-Adsorbed 1 Mg

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Catalog Number: (10150-802)

Supplier: Immunoreagents

Description: ImmunoReagents is a manufacturer of quality research and production reagents for the Life Science Industries. Product lines include a wide range of antibodies used in ELISA, immunohistochemistry (IHC), western blotting, flow cytometry (FACS), immunofluorescence and microscopy.  Antibodies produced cover a broad range of Immunoglobulins from various species cross absorbed to provide high specificity.  

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Supplier: Rockland Immunochemical

Description: This affinity purified antibody has been tested for use in ELISA and western blotting using M1 cells which express endogenous wild-type c-Myb Protein and in COS7 cells transfected with c-Myb.

Catalog Number: (RL010-0602)

Supplier: Rockland Immunochemical

Description: Produced through a multi-stage process that includes delipidation, salt fractionation, ion-exchange chromatography, gel filtration, and affinity chromatography. No contaminating proteins are observed when assayed at a protein concentration of 20mg/mL against anti-whole serum or anti-fragment specific antisera. All immunoglobulin fragments are prepared from highly purified, whole molecules subject to enzymatic digestion.

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Catalog Number: (RL600-401-F85)

Supplier: Rockland Immunochemical

Description: Anti-KDEL Antibody is suitable for use in WB and IHC. Specific conditions for reactivity should be optimized by the end user.

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Catalog Number: (76634-538)

Supplier: Diagnostic Biosystems

Description: This antibody recognizes keratin polypeptide of 54 kDa. It stains a number of epithelial cells including ductal and glandular epithelia. Stratified squamous epithelia are positive but transitional epithelium of the urinary tract does not show any staining. This antibody labels adenocarcinomas and transitional carcinomas but does not react with squamous cell carcinomas.

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Catalog Number: (RL707-401-002)

Supplier: Rockland Immunochemical

Description: Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring extremely low background levels, absence of F(c) mediated binding, lot-to-lot consistency, high titer and specificity.

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Catalog Number: (RL200301I34)

Supplier: Rockland Immunochemical

Description: Anti-TRF2 Antibody is suitable for use in ChIP, ELISA, Flow (Intracellular) Cytometry, IF/ICC, Immunochemistry(frozen), IP, and WB. Expect a band approximately 55.6 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

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