You Searched For: Antibodies

Supplier: Enzo Life Sciences

Description: Fodrin, also referred to as non-erythroid (αII-; brain) spectrin, is a tetrameric (αγ)2 actin-binding, fibrous protein, widely distributed in vertebrates, which forms part of the sub-membranous cytoskeleton within many cell types including neurons, and is particularly abundant with axons. The α-subunits of fodrins and spectrin are highly conserved phylogenetically, with the exception of human α-fodrin, which shares only 55-59% homology with erythroid-specific α-spectrins. The β-subunits of spectrin (and γ-subunits of fodrins) are species specific. The interleukin-1 converting enzyme (ICE) family of proteases has been implicated as important effectors of the apoptotic pathway, perhaps acting hierarchically in a protease cascade. Neuronal fodrin is known to be cleaved by calpain following ischaemic insult and it has been proposed that calpain and an unidentified protease play a role in the onset of neuronal death following transient forebrain ischaemia. Recently, an ICE-like protease has been implicated in the early cleavage of fodrin, producing a 150kDa fragment, proximal to CPP32 in Fas-induced and C2-ceramide mediated apoptosis. A cleavage product of α-fodrin has been proposed as a candidate autoantigen in primary Sjögren’s syndrome and α-fodrin has been shown to be the source of a so-called ‘inhibitory protein factor’ family, members of which have been shown to inhibit both GABA and ATP-dependent glutamate uptake into purified synaptic vesicles.

Catalog Number: (ABCA_AB9829-100UG)

Supplier: ABCAM INC.

Description: Anti-Macrophage Inflammatory Protein 3 alpha Rabbit Polyclonal Antibody

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Catalog Number: (ABCA_AB131537-100U)

Supplier: ABCAM INC.

Description: Anti-SHP1 Rabbit Polyclonal Antibody

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Catalog Number: (ABCA_AB310482-100U)

Supplier: ABCAM INC.

Description: Anti-HDAC9 Rabbit Monoclonal Antibody [clone: EPR5223] (Alexa Fluor® 594)

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Supplier: ABCAM INC.

Description: Anti-HOOK2 Rabbit Monoclonal Antibody [clone: EPR8673]

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Catalog Number: (ABCA_AB154226-100U)

Supplier: ABCAM INC.

Description: Anti-SmarcAL1 Rabbit Polyclonal Antibody

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Catalog Number: (ABCA_AB241068-100U)

Supplier: ABCAM INC.

Description: Anti-non-muscle Myosin IIA Rabbit Polyclonal Antibody

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Supplier: Rockland Immunochemical

Description: The emission spectra for this ATTO conjugate matches the principle output wavelengths of most common fluorescence instrumentation.

Supplier: Diagnostic Biosystems

Description: This antibody reacts with the heavy chain present in all types of human IgM. It stains B cell follicles in human lymphoid tissues. In lymphoid tissues, IgM containing plasma cells stain strongly but immune complexes are usually undetectable.

Catalog Number: (ABCA_AB190260-100U)

Supplier: ABCAM INC.

Description: Anti-CSNK1G1 Rabbit Polyclonal Antibody

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Catalog Number: (ABCA_AB231662-100U)

Supplier: ABCAM INC.

Description: Anti-CALCB Rabbit Polyclonal Antibody

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Catalog Number: (75930-788)

Supplier: Rockland Immunochemical

Description: PEN2, in addition to presenilin, nicastrin, and APH-1 forms the gamma-secretase protein complex, a membrane-bound aspartyl protease that can cleave certain proteins at peptide bonds buried within the hydrophobic environment of the lipid bilayer. This cleavage is responsible for a key step in signaling from several cell-surface receptors and is thought to be required for the generation of the neurotoxic amyloid peptides that are central to the pathogenesis of Alzheimer's disease. Like the tumor necrosis factor-alpha-converting enzyme (TACE) and the beta-site cleavage enzyme (BACE) protease families, gamma-secretase will cleave the amyloid precursor protein (APP), but within the intramembrane region of APP, resulting in either the non-toxic p3 (from the alpha and gamma cleavage site) or the toxic Abeta amyloid peptide (from the beta and gamma cleavage site). It is thought that accumulation of the Abeta peptide is the precursor to Alzheimer's disease.

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Catalog Number: (ABCA_AB272066-100U)

Supplier: ABCAM INC.

Description: Anti-CD163 Rabbit Monoclonal Antibody [clone: BLR087G]

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Supplier: ABCAM INC.

Description: Anti-TAK1 (phospho S439) Rabbit Monoclonal Antibody [clone: EPR2863]

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Catalog Number: (ABCA_AB171799-50UG)

Supplier: ABCAM INC.

Description: Anti-RND3 Mouse Polyclonal Antibody

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Catalog Number: (RL610-443-002)

Supplier: Rockland Immunochemical

Description: The emission spectra for this DyLight® conjugate match the principle output wavelengths of most common fluorescence instrumentation.

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