You Searched For: viral+rna

Description: Secondary antibody reagents are ideal for western blotting, immunochemistry, ELISA, Fluorescence Microscopy, Flow Cytometry as well as other antibody detection methods.

Catalog Number: RL605-4602

Supplier: Rockland Immunochemical

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Description: The potassium channel, subfamily K, member 1 (KCNK1), is member of the superfamily of potassium channel proteins containing two pore-forming P domains (1,2). KCNK1 is a ubiquitous human weakly inward rectifying K+ channel that is widely expressed in human tissues, and particularly abundant in brain and heart (1). Both KCNK1 and the related protein KCNK2 contribute significantly to the passive conductance of hippocampal astrocytes (3).

Catalog Number: 75929-410

Supplier: Rockland Immunochemical

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Description: Anti-Histone H3 [Monomethyl Lys4] antibody is useful for Western Blot, Immunocytochemistry, Immunofluorescence, Chromatin Immunoprecipitation, and Dot Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximatel

Catalog Number: RL600401I57

Supplier: Rockland Immunochemical

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Description: DnaK possesses an autophosphorylation activity and a weak 5-nucleotidase activity, cleaving the 5 phosphate groups from both ribose and deoxyribose nucleotides. The role of DnaK in ATP-dependent protein-protein interactions has been extended to normal E. coli physiology, where, like eukaryotic Hsp70 homologs, it is thought to participate in the assembly/disassembly of protein complexes.

Catalog Number: 200062-782

Supplier: Enzo Life Sciences

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Description: The estrogen receptor-related factor (ERRF) is a recently identified protein whose expression is upregulated in multiple cell lines and primary breast cancer tumors. Increased ERRF expression was significantly associated with ER or progesterone receptor (PR) positivity even in HER2-negative tumors. This higher ERRF expression correlated with better disease-free survival and overall survival. In two ER-positive breast cancer cell lines, knockdown of ERRF suppressed cell growth in vitro and tumorigenesis in xenograft models, suggesting that ERRF plays a role in estrogen-ER-mediated breast cancer cell growth and may thus be a potential therapeutic target.

Catalog Number: 10802-628

Supplier: Rockland Immunochemical

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Description: The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promoters and alternative splicing. UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from DNA that arise through either misincorporation during replication or cytosine deamination. UNG2 can also be bound by the HIV-1 integrase and incorporated into the virion particle, suggesting that it is required to remove uracils from the viral genome. As the intrinsic antiviral protein APOBEC3G generates numerous uracils in the HIV genome during its replication, it may be that the UNG2 contributes to the APOBEC3G-mediated loss of infectivity by generating abasic sites in the viral genome.

Catalog Number: 75933-450

Supplier: Rockland Immunochemical

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Description: The matrix metalloproteinase 16(MMP16) protein consists of 604 amino acids and has a characteristic MMP domain structure, which gene is mapped on human chromosome 8q21. Additionally, MMP16 has a C-terminal extension containing a potential transmembrane domain, similar to MMP14 , MMP15 , and MMP17. Furthermore, it is membrane-bound and is a member of the membrane-type MMPs that are a subclass in the MMP family since the other members lack a C-terminal transmembrane domain and are secreted as soluble forms. MMP16 is expressed as a 12-kb transcript in brain, placenta, heart, and some carcinoma cell lines, but is not detectably expressed in lung, kidney, liver, spleen, and muscle. This antibody is suitable for researchers interested in cancer research.

Catalog Number: 75929-964

Supplier: Rockland Immunochemical

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Description: Suitable for immunoprecipitation, immunodiffusion, conjugation and most immunological methods requiring lot-to-lot consistency, high titer and specificity. Optimal concentrations in other immunoassays should be determined by the researcher.

Catalog Number: RL600-101-098

Supplier: Rockland Immunochemical

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Description: The ImmunoReagents' DyLight® 550 conjugates provide vibrant orange-to-red fluorescence with better performance than other rhodamine derivatives, including Alexa Fluor 555, TRITC and Cy3 for fluorescent applications. DyLight® 550 conjugates have tight excitation/emission spectra that are ideal for multicolor applications. DyLight® 550 conjugated secondary antibodies are used in fluorescence microscopy, flow cytometry, Western blotting, ELISA, high-content screening and other array platforms. Excitation/Emission = 562nm / 576nm Emission Color = Orange to Red (Similar Dyes: Alexa Fluor 555, Cy3, TRITC)

Catalog Number: 10150-320

Supplier: Immunoreagents

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Description: Recommended Applications: Flow Cytometry, IHC (FS), IHC (PS), IP

Species reactivity: Human, Dog

Catalog Number: 76002-818

Supplier: Enzo Life Sciences

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Description: The RM2-5 antibody reacts with mouse CD2, an approximately 50 kDa glycoprotein, and a member of the Ig superfamily. CD2, also known as LFA-2, is a receptor for CD48 in the mouse and is expressed on the cell surface of all lymphocytes. CD2 mediates cell to cell adhesion and is involved in T cell activation.

Catalog Number: 10208-678

Supplier: Tonbo Biosciences

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Description: Suitable for ELISA, immunohistochemistry, immunoprecipitation and Wstern blotting. Detects endogenous levels of total Akt protein. This antibody does not cross-react with other related proteins.

Catalog Number: RL200-301-401

Supplier: Rockland Immunochemical

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Description: MDA (Malondialdehyde) is a highly reactive three carbon dialdehyde produced as a byproduct of polyunsaturated fatty acid peroxidation and arachidonic acid metabolism. MDA readily combines with several functional groups on molecules including proteins, lipoproteins, and DNA. MDA modified proteins may show altered physico-chemical behavior and antigenicity. Antibodies to MDA will help to visualize the MDA-adducts.

Catalog Number: 89146-212

Supplier: Enzo Life Sciences

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Description: Recommended Applications: Flow Cytometry

Species reactivity: Human, Dog

Catalog Number: 76002-814

Supplier: Enzo Life Sciences

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Description: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals; however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species-jumping ability.

Catalog Number: 10800-264

Supplier: Rockland Immunochemical

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Description: The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma/delta protein chains, known as the g/d TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can result in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the g/d TCR.

Catalog Number: 75834-308

Supplier: Tonbo Biosciences

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