You Searched For: Antibodies

Catalog Number: (RL712-401-002)

Supplier: Rockland Immunochemical

Description: Suitable for immunomicroscopy and flow cytometry or FACS analysis as well as other antibody based fluorescent assays requiring extremely low background levels, absence of F(c) mediated binding, lot-to-lot consistency, high titer and specificity.

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Catalog Number: (89161-844)

Supplier: Enzo Life Sciences

Description: Host: Rabbit

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Supplier: Tonbo Biosciences

Description: The OKT3 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Catalog Number: (75931-388)

Supplier: Rockland Immunochemical

Description: PTPRD (Protein tyrosine phosphatase receptor type D) is a member of the protein tyrosine phosphatase (PTP) family that plays diverse roles during development including cell growth, differentiation, mitotic cycle and oncogenic transformation. PTPRD contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. The extracellular region of PTPRD is composed of three Ig-like and eight fibronectin type III-like domains (1,3). PTPRD interacts with PPFIA1-3 and is a tumor suppressor on chromosome 9p that is involved in the development of glioblastoma multiforme (GBMs) and multiple human cancers.

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Catalog Number: (10151-606)

Supplier: Immunoreagents

Description: The ImmunoReagents' DyLight® 550 conjugates provide vibrant orange-to-red fluorescence with better performance than other rhodamine derivatives, including Alexa Fluor 555, TRITC and Cy3 for fluorescent applications. DyLight® 550 conjugates have tight excitation/emission spectra that are ideal for multicolor applications. DyLight® 550 conjugated secondary antibodies are used in fluorescence microscopy, flow cytometry, Western blotting, ELISA, high-content screening and other array platforms. Excitation/Emission = 562nm / 576nm Emission Color = Orange to Red (Similar Dyes: Alexa Fluor 555, Cy3, TRITC)

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Catalog Number: (RL100-401-E46)

Supplier: Rockland Immunochemical

Description: Anti-TR4 (Rabbit) is suitable for use in Western Blotting. Anti-TR4 antibodies are specific for the ~64 kDa TR4 Protein by Western blot in cerebellum and nuclear extracts from MEL cell lines. Reactivity is expected from human and rat.

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Catalog Number: (RL612-401-D24)

Supplier: Rockland Immunochemical

Description: Anti-DARPP-32 (Rabbit) Antibody is suitable for use in ELISA, Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a band of approximately 32 kDa in size corresponding to DARPP 32 Protein in the appropriate cell lysate.

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Catalog Number: (76634-348)

Supplier: Diagnostic Biosystems

Description: This antibody is specific to α-smooth muscle isoform of actin. It reacts with smooth muscle cells of vessels and different parenchymes. This antibody does not cross-react with β and γ-cytoplasmic, α-sarcomeric and α-myocardial actin isoforms.

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Supplier: Tonbo Biosciences

Description: The RPA-T4 antibody reacts with human CD4, a 59 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta-2 domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4, and co-receptors CCR5 and CXCR4, may also be utilized by HIV-1 to enter T cells. Human CD4 is typically expressed on thymocytes, some mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.

Supplier: Tonbo Biosciences

Description: The Human Basic B Lymphocyte backbone panel is a six-color combination of anti-human antibodies. This panel can serve as a backbone to identify the various B lymphocyte subsets, including naive, memory and plasma cells. This panel configuration leaves room for GFP or additional drop-in markers, if desired. Violet laser (405 nm) required for detection of CD45 violetFluoTM 450.

Catalog Number: (RL200-301-383S)

Supplier: Rockland Immunochemical

Description: This antibody is optimally suited for monitoring the expression of FLAG® tagged fusion Proteins. As such, this antibody can be used to identify fusion Proteins containing the FLAG® epitope.

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Catalog Number: (75933-286)

Supplier: Rockland Immunochemical

Description: TNF-related weak inducer of apoptosis (TWEAK) is a member of the tumor necrosis factor superfamily (TNFSF) of structurally related cytokines. Like most other members of this family, TWEAK is a cell surface-associated type II transmembrane protein although a smaller, biologically active form can also be generated by cleavage near the cell membrane. TWEAK has multiple biological activities, including stimulation of cell growth and angiogenesis, induction of inflammatory cytokines, in addition to stimulation of apoptosis. The TWEAK signal transduction pathway has not been well established but it appears to signal via TweakR/Fn14 in a manner similar to that described for other TNFSF members that bind receptors lacking death domains.

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Catalog Number: (76201-846)

Supplier: Enzo Life Sciences

Description: Recommended Applications: Flow Cytometry, IHC (PS), WB, Fluorescence microscopy

Species reactivity: Human

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Catalog Number: (75931-704)

Supplier: Rockland Immunochemical

Description: RUSC2, also known as Iporin, shares with the related protein RUSC1 a common domain structure of RUN, leucine zipper and SH3 domain in addition to over 30% amino acid identity. RUSC2 is a rab1-interacting protein that also interacts with GM130, another rab1-interacting protein. RUSC2 interacts with specific rab1 isoforms with different rab-binding specificity. It has been suggested that RUSC2 may function as a link between the targeting of ER derived vesicles triggered by the rab1 GTPase and a signaling pathway composed of proteins containing SH3 and/or poly-proline regions.

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Catalog Number: (75930-934)

Supplier: Rockland Immunochemical

Description: The PIAS (protein inhibitor of activated STAT) proteins play a crucial role as transcriptional coregulators in various cellular pathways, including the STAT, p53 and the steroid hormone signaling pathway. The PIAS protein family includes at least five evolutionarily conserved genes, including PIAS3. The major function of the PIAS proteins is the control of gene transcription and can also act as small ubiquitin-like-modifier (SUMO) E3 ligases. PIAS3 binds specifically to STAT3 following the stimulation of STAT3. Increased expression of PIAS3 has been observed in several human cancers, including lung, breast, and brain tumors, but not in anaplastic lymphoma kinase-positive T/null-cell lymphomas, indicating that PIAS3 plays multiple roles in different tissue and cell types.

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Catalog Number: (RL200401H57)

Supplier: Rockland Immunochemical

Description: Anti-ATG8 antibody is suitable for use in Immunochemistry(p) and WB. Expect a band approximately 16 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

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