You Searched For: Antibodies

Catalog Number: (10147-360)

Supplier: Azure Biosystems

Description: Goat-anti-guinea pig secondary antibody, AzureSpectra 700 conjugated secondary antibody for fluorescent Westerns - 250ul

SDS Sale

Catalog Number: (75794-866)

Supplier: Azure Biosystems

Description: Azure’s high-quality HRP-conjugated secondary antibodies offer unparalleled sensitivity and performance for immunoblotting and ELISA applications. Optimized to work with Azure's Radiance and Radiance Plus detection systems.

SDS Sale

Catalog Number: (75794-880)

Supplier: Azure Biosystems

Description: Goat-anti-chicken secondary antibody, Conjugate: AzureSpectra 550, Application: fluorescent Westerns, Size: 250 ul

SDS Sale

Catalog Number: (ABCA_AB308934-200U)

Supplier: ABCAM INC.

Description: Anti-Prion protein PrP Rabbit Monoclonal Antibody [clone: EP1802Y] (Alkaline Phosphatase)

New Product Sale

Supplier: Enzo Life Sciences

Description: Synuclein was originally identified in Torpedo californica as a small neuroprotein that localized to the nuclear envelope of neurons and to presynaptic nerve termini. The human homolog was initially termed NACP, a precursor protein to NAC (Non-Ab Component), because of its prevalence in amyloid plaques in Alzheimer’s patients. Later, NACP was recognized as being alpha-Synuclein (alpha-SYN), a 14kDa protein, belonging to the synuclein family of phosphoproteins that also includes: betalpha-SYNuclein, gammalpha-SYNuclein, and synoretin.
alpha-SYN is recognized as a key component in the development and diagnosis of neurodegenerative synucleinopathic diseases (NSDs), such as Alzheimer’s and Parkinson’s disease. In the past five years, several genetic and post-translational modifications to alpha-SYN have been elucidated that have been linked to its collaboration in the formation of the classical Lewy bodies (LBs) or Lewy neurites that are associated with neurodegeneration. A study that shed more light on the neurogenesis of autorecessive synucleinopathies (ARSs) was the finding that alpha-SYN accumulation can occur due to mutations in the E3 ubiquitin ligase.
ARSs only account for a small percentage of NSD. Thus the illustration that alpha-SYN has a high susceptibility to tyrosine nitration may be the key component in understanding the formation of LBs. Due to the chemical structure of alpha-SYN, tyrosine nitration readily leads to the formation of oligomers via covalent O,O’-dityrosine bonds (cross-linking). Nitrosylated, wild-type, alpha-SYN products thus form SDS-insoluble, heat-stable aggregates in vitro that may account for alpha-SYN inclusions in all forms of NSDs.

Catalog Number: (ABCA_AB315188-100U)

Supplier: ABCAM INC.

Description: Anti-68kDa Neurofilament/NF-L Mouse Monoclonal Antibody [clone: 1B11]

New Product Sale

Catalog Number: (76284-860)

Supplier: Enzo Life Sciences

Description: Recombinant monclonal antibody (Rat IgG1λ).

Recommended Applications: Flow Cytometry, WB

Sale

Catalog Number: (101410-454)

Supplier: Enzo Life Sciences

Description: Smac/DIABLO is one of the pro-apoptotic proteins normally found in the intermembrane space of the mitochondria. In response to apoptotic stimuli, Smac/DIABLO is released into the cytosol resulting in permeabilization of the mitochondrial membrane. Cytosolic Smac/DIABLO activates caspase-9 by binding IAP proteins. Changes in the expression level of Smac/DIABLO have been demonstrated in a number of human cancers including melanoma, ovary, and prostate.

Sale

Catalog Number: (ABCA_AB173825-50UL)

Supplier: ABCAM INC.

Description: Anti-HA tag Mouse Monoclonal Antibody [clone: 2-2.2.14] (Biotin)

New Product Sale

Supplier: ABCAM INC.

Description: Anti-Cardiac Troponin T Rabbit Monoclonal Antibody [clone: EPR20266] (PE)

New Product

Catalog Number: (ABCA_AB320195-100U)

Supplier: ABCAM INC.

Description: Anti-SF3B1 Rabbit Monoclonal Antibody [clone: EPR11986] (APC)

New Product Sale

Catalog Number: (ABCA_AB272078-100U)

Supplier: ABCAM INC.

Description: Anti-LAG-3 Rabbit Monoclonal Antibody [clone: BLR027F]

New Product Sale

Catalog Number: (RL600-144-098)

Supplier: Rockland Immunochemical

Description: The emission spectra for this DyLight® conjugate match the principle output wavelengths of most common fluorescence instrumentation.

Sale

Catalog Number: (ABCA_AB117625-50UG)

Supplier: ABCAM INC.

Description: Anti-SCUBE2 Rabbit Polyclonal Antibody

New Product Sale

Supplier: Enzo Life Sciences

Description: The human Cullin family of genes consists of Cul-1, Cul-2, Cul-3, Cul-4a, Cul-4b, and Cul-5. Among the 6 members, Cul-1 and Cul-2 are very well characterized. Cul-2 is homologous to the Saccharomyces cerevisiae cdc53 gene. Studies have shown that Cul-1 forms an E3 ubiquitin-ligase, called the SCF complex (Skp1 and F-box protein such as bTrCp or FWD1), which controls the proteolysis of G1 cell cycle regulatory proteins.

Catalog Number: (89141-464)

Supplier: Enzo Life Sciences

Description: The conversion of arachidonic acid to prostaglandin H2 (PGH2) by cyclooxygenase (COX) enzymes is the first step in the synthesis of prostanoids. Prostaglandin D2 (PGD2) is synthesized from PGH2 by the action of PGD synthase, and its actions in vasodilation and platelet activation are mediated via activation of two identified G-protein coupled receptors (GPCRs): DP1 and DP2 (formerly CRTH2). Both DP1 and DP2 receptors are coupled to Gs alpha subunits, resulting in increased adenylyl cyclase activity and cAMP production upon agonist binding. DP1 receptor is expressed moderately in the ileum and weakly in the lung, stomach, and uterus of mice, and weakly in the small intestine of humans. In rodents, expression of PGD synthase and the DP1 receptor is seen in the leptomeninges, where it is believed they play a role in the induction of sleep. The DP1 receptor may also oppose DP2-mediated activation of basophils, eosinophils, and Th2 cells.

Sale