You Searched For: Antibodies

Catalog Number: (75929-726)

Supplier: Rockland Immunochemical

Description: LRRK2 is a large protein with multiple domains including several ankyrin, leucine-rich, and WD40 repeats, a Ras-like small GTPase family domain named Roc, and a kinase domain that is closely related to the RIP kinase domain. LRRK2 gene is expressed in brain as well as in other tissues such as lung, liver and heart. LRRK2 might be central to the pathogenesis of several major neurodegenerative diseases associated with parkinsonism. Several dominantly inherited missense mutations in the gene encoding LRRK2 have been identified in several families that exhibit a broad spectrum of neuropathological features. Anti-LRRK2 is ideal for researchers interested in Neuroscience, specifically parkinsonism, as well as pathways related to the Electron Transport Chain and Wnt Signaling.

Sale

Catalog Number: (75933-784)

Supplier: Rockland Immunochemical

Description: Childhood and adult obesity in the United States and to a lesser extent the rest of the world has increased dramatically over the past decade. Both environmental and genetic factors are involved in the onset and progression of weight gain. Recently, the potassium channel KCTD15 was identified as a genetic loci associated with higher than normal body mass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Further studies on single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still significantly associated with higher than normal BMI levels. At least two isoforms of KCTD15 are known to exist.

Sale

Catalog Number: (RL600-103-387)

Supplier: Rockland Immunochemical

Description: Suitable for immunoblotting (western or dot blot), ELISA, immunoperoxidase electron microscopy and immunochemistry as well as other peroxidase-antibody based enzymatic assays requiring lot-to-lot consistency.

Sale

Catalog Number: (10800-886)

Supplier: Rockland Immunochemical

Description: Coronins, such as Coronin 7, constitute an evolutionarily conserved family of WD-repeat actin-binding proteins whose function is thought to be regulating the cytoskeleton. Unlike other cytoplasmically localized Coronins, Coronin 7 localizes in part to the Golgi complex and is thought to play a role in Golgi complex morphology and function. Other experiments indicate that Coronin 7 interacts with the anti-proliferative protein TOB1 and enhances its degradation though the SCF ubiquitin ligase (E3) complex.

Sale

Supplier: Tonbo Biosciences

Description: The M1/70 antibody reacts with human and mouse CD11b, also known as integrin alpha M. This 165-170 kDa cell surface glycoprotein is part of a family of integrin receptors that mediate adhesion between cells (cell-cell) and components of the extracellular matrix, e.g. fibrinogen (cell-matrix). In addition, integrins are active signaling receptors which recruit leukocytes to inflammatory sites and promote cell activation. Complete, functional integrin receptors consist of distinct combinations of integrin chains which are differentially expressed. Integrin alpha M (CD11b) assembles with Integrin beta-2 (CD18) into a receptor known as Macrophage Antigen-1 (Mac-1) or complement receptor type 3 (CR3). This receptor binds and induces intracellular signaling through ICAM-1 on endothelial cells and can also facilitate removal of iC3b bearing foreign cells.

Catalog Number: (RL600-401-394)

Supplier: Rockland Immunochemical

Description: This antibody is suitable for western blotting, immunoprecipitation, and ELISA.  This antibody detects mouse Mcl-1 and is not expected to cross react with the human sequence.  Cross reactivity with Mcl-1 from other sources is unknown.

Sale

Catalog Number: (RL007-0004)

Supplier: Rockland Immunochemical

Description: 1mg. Antibody Concentration: 1 mg/mL. Fluorochrome/Protein: 3.8 moles TRITC per mole of hamster IgG. Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: 10 mg/mL BSA IgG and protease free. For research. Lyophilized.

Sale

Catalog Number: (76634-294)

Supplier: Diagnostic Biosystems

Description: This antibody is specific to human prostatic acid phosphatase. It reacts with the glandular epithelium of normal and hyperplastic prostate and with prostate adenocarcinoma.

Sale

Supplier: Tonbo Biosciences

Description: The UCHT1 antibody is specific for human CD3e, also known as CD3 epsilon, a 20 kDa subunit of the T cell receptor complex, along with CD3 gamma and CD3 delta. These integral membrane protein chains assemble with additional chains of the T cell receptor (TCR), as well as CD3 zeta chain, to form the T cell receptor – CD3 complex. Together with co-receptors CD4 or CD8, the complex serves to recognize antigens bound to MHC molecules on antigen-presenting cells. These interactions promote T cell receptor signaling (T cell activation), inducing cell proliferation, differentiation, production of cytokines or activation-induced cell death. CD3 is differentially expressed during thymocyte-to-T cell development and on all mature T cells.

Catalog Number: (RL709-1112)

Supplier: Rockland Immunochemical

Description: Suitable for highly specific immunological methods requiring extremely low background levels, absence of F(c) mediated binding, lot-to-lot consistency, high titer and specificity.

Sale

Catalog Number: (RL607-4904)

Supplier: Rockland Immunochemical

Description: Secondary Rabbit Anti-IgG F(ab')2 Reacts with Hamster

Sale

Catalog Number: (RL609-4606)

Supplier: Rockland Immunochemical

Description: This product has been assayed against 1.0 µg of Human IgA in a standard capture ELISA using Peroxidase Conjugated Streptavidin and ABTS (2,2’-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid])

Sale

Catalog Number: (89145-282)

Supplier: Enzo Life Sciences

Description: Host: Rabbit

Sale

Catalog Number: (RL600-401-996)

Supplier: Rockland Immunochemical

Description: Cancer Research. Cell Signaling. Cell Cycle Cell Signaling Primary Antibody. Cyclin-Dependent Kinase 9 (CDK9) pT29 functional in Western Blot ELISA & IP reactivity to Human Mouse Rat. Size 100ug.

Sale

Catalog Number: (10152-274)

Supplier: Immunoreagents

Description: ImmunoReagents’ FITC Conjugates are used in immunofluorescence microscopy, flow cytometry, FLISA (fluorescent ELISA) and high throughput screening assays. Fluorescein is typically excited by the 488 nm line of an argon laser, and emission is collected at 518 nm. FITC antibody conjugates are yellow-orange in color but emit a yellow-green color upon Em 518 nm. FITC antibody conjugates are sensitive to light. The typical FITC to antibody ratio (F/P) is >4.0 Excitation/Emission = 494nm / 518nm Emission Color = Green (Similar Dyes: Alexa Fluor 488, Cy2, DyLight ® 488)

Sale

Catalog Number: (10151-116)

Supplier: Immunoreagents

Description: The ImmunoReagents' DyLight® 550 conjugates provide vibrant orange-to-red fluorescence with better performance than other rhodamine derivatives, including Alexa Fluor 555, TRITC and Cy3 for fluorescent applications. DyLight® 550 conjugates have tight excitation/emission spectra that are ideal for multicolor applications. DyLight® 550 conjugated secondary antibodies are used in fluorescence microscopy, flow cytometry, Western blotting, ELISA, high-content screening and other array platforms. Excitation/Emission = 562nm / 576nm Emission Color = Orange to Red (Similar Dyes: Alexa Fluor 555, Cy3, TRITC)

Sale