You Searched For: pressure+hose

Catalog Number: (10800-502)

Supplier: Rockland Immunochemical

Description: Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-beta (Abeta) peptides produced by the endoproteolysis of the amyloid precursor protein (APP). The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Abeta levels. While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link. CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.

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Catalog Number: (75931-766)

Supplier: Rockland Immunochemical

Description: The mitochondrial succinate dehydrogenase complex subunit D (SDHD) is one of four proteins that make up the tricarboxylic cycle enzyme succinate dehydrogenase (SCH). Studies have shown that mutations in SDHD often leads to hereditary paragangliomas, usually benign tumors of the autonomic nervous system, suggesting that SDHD also plays a role as a tumor-suppressor gene. In one family with a nonsense mutation (R22X) in the SDHD gene, a loss of heterozygosity was found in the paragangliomas, and within these tumors the enzymatic activity of Complex II in the mitochondrial respiratory chain was completely abolished. Furthermore, high levels of angiogenic factors EPAS1 and VEGF was observed, which may stimulate tumor growth.

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Catalog Number: (75930-994)

Supplier: Rockland Immunochemical

Description: PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit), also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase class III), is a member of the PI3/PI4-kinase family (1). It is a catalytic subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate and ubiquitously expressed with a highest expression in skeletal muscle (1,2). PIK3C3 is involved in the endosome to lysosome transport and plays important roles in intracellular membrane trafficking and autophagy (3-5).

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Catalog Number: (RL605-403-B69)

Supplier: Rockland Immunochemical

Description: Recommended Dilutions: ELISA: 1:120000; Western Blot: 1:2000 - 1:20000; Immunochemistry: 1:1000 - 1:5000
Restore with deionized water (or equivalent); 1.0 ml
Do not add Sodium Azide!

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Catalog Number: (RL013-0902)

Supplier: Rockland Immunochemical

Description: 1mg. Antibody Concentration: 1 mg/mL. Fluorochrome/Protein: 2.3 moles Texas Red per mole of Sheep IgG. Buffer: 0.02M potassium phosphate, 0.15M sodium chloride, pH 7.2. Stabilizer: 10 mg/mL Bovine Serum Albumin IgG and protease free. Lyophilized.

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Catalog Number: (RL614-4302)

Supplier: Rockland Immunochemical

Description: Suitable for immunoblotting (western or dot blot), ELISA, immunoperoxidase electron microscopy and immunochemistry as well as other peroxidase-antibody based enzymatic assays requiring lot-to-lot consistency.

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Catalog Number: (RL600401J29)

Supplier: Rockland Immunochemical

Description: Anti-Protein Kinase C Delta-Binding Protein (Rabbit) Antibody Is Useful For ELISA, Immunohistochemistry, And Western Blot. Specific Conditions For Reactivity Should Be Optimized By The End User.

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Catalog Number: (75931-130)

Supplier: Rockland Immunochemical

Description: Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide (NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. Knockdown experiments indicated that this protein is involved with multiple cell signaling pathways, including the JAK-Stat3, MAP kinase, and PKC pathways. PPAPDC1B may also potentiate the estrogen receptor pathway by down-regulating DUSP22.

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Catalog Number: (RL709-1118)

Supplier: Rockland Immunochemical

Description: Antibody Anti-Human IgG F(ab')2 is suitable for immunoblotting (western or dot blot), ELISA, and immunochemistry as well as other peroxidase-antibody based enzymatic assays requiring lot-to-lot consistency.

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Supplier: Rockland Immunochemical

Description: This Protein-A purified antibody has been tested for use in Western blotting. Specific conditions for reactivity should be optimized by the user. Expect a band approximately 35.4 kDa in size corresponding to Borrelia burgdorferi p39 Protein by Western blotting.

Catalog Number: (10801-890)

Supplier: Rockland Immunochemical

Description: Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated APRIL (for a proliferation-inducing ligand), TALL-2 (for TNF- and ApoL-related Leukocyte-expressed Ligand 2), and TRDL-1a (for TNF related death ligand 1a) in human and mouse. Two receptors for APRIL were recently identified and designated TACI and BCMA. APRIL stimulates B and T cell proliferation, triggers humoral immune responses, activates NF-kB, and induces cell death. APRIL and its close relative of BlyS and their receptors BCMA and TACI are involved in diseases of autoimmunity and cancer.

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Catalog Number: (10152-386)

Supplier: Immunoreagents

Description: ImmunoReagents’ Horseradish Peroxidase (HRP) antibody conjugates are the most popular conjugates due to their high level of sensitivity, stability, and low costs. HRP conjugates are an ideal choice for use in ELISA, Immunohistochemistry (IHC), and Western blotting experiments.

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Catalog Number: (10800-978)

Supplier: Rockland Immunochemical

Description: Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases. Certain serine/threonine protein kinases, such as RIP and DAP kinase, are mediators of apoptosis. DAP kinase (DAPK) is pro-apoptotic calcium-regulated serine/threonine kinase containing death domain. Ectopic expression of DAPK induces cell death and suppresses oncogenic transformation. DAPK mediates IFN-gamma induced apoptosis. A novel DAP kinase-related protein was recently identified and designated DAPK2 and DRP-1. Ectopicly expressed DAPK2 induced apoptosis in various types of cells. DAPK has high sequence homology to ZIP kinase and DRAK1/2, and they represent a novel family of serine/threonine kinases, which mediates apoptosis through their catalytic activities. The messenger RNA of DAPK2 is expressed in multiple human tissues.

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Catalog Number: (RL200-401-909)

Supplier: Rockland Immunochemical

Description: This Protein A purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a predominant band approximately 90-180 kDa in size corresponding to RREB1 by western blotting.

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Catalog Number: (RL200-4357S)

Supplier: Rockland Immunochemical

Description: Anti-Carbonic anhydrase II has been assayed against 1.0 µg of Carbonic Anhydrase II (Bovine Erythrocytes) in a standard capture ELISA using ABTS (2,2’-azino-bis-[3-ethylbenthiazoline-6-sulfonic acid])

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Catalog Number: (89153-170)

Supplier: Enzo Life Sciences

Description: Host: Mouse, Isotype: IgG2b

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