You Searched For: Antibodies

Catalog Number: (75783-578)

Supplier: Immunoreagents

Description: GACRP-30 IgG (H&L) Antibody, Affinity Pure, Host: Rabbit, Species Reactivity: Human, Concentration: 1.0 mg/ml, Form: Lyophilized, Purification: Affinity purified using solid phase biotin, Applications: Immunoassay, Storage: 2-8 deg C, For in vitro Laboratory Use

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Catalog Number: (RL100-401-G35)

Supplier: Rockland Immunochemical

Description: Anti-Rab4 Antibody is suitable for use in WB and Immunofluorescence microscopy. Expect a band approximately ~26kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

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Supplier: Diagnostic Biosystems

Description: This antibody is specific against an epitope located on the β chain (i.e. in S-100a and S-100b) but not on the α chain of S-100 (i.e. in S-100a and S-100ao). This antibody can be used to localize S-100a and S-100b in various tissue sections.

Catalog Number: (10150-590)

Supplier: Immunoreagents

Description: ImmunoReagents is a manufacturer of quality research and production reagents for the Life Science Industries. Product lines include a wide range of antibodies used in ELISA, immunohistochemistry (IHC), western blotting, flow cytometry (FACS), immunofluorescence and microscopy.  antibodies produced cover a broad range of Immunoglobulins from various species cross absorbed to provide high specificity.  

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Supplier: Tonbo Biosciences

Description: The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

Catalog Number: (75932-164)

Supplier: Rockland Immunochemical

Description: The sterol regulatory element binding transcription factor 1 (SREBF1) is a transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis (1). The related protein SREBF2 also binds SRE1 and activates transcription in an additive fashion to SREBF1 (2). SREBF1 is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription by binding to the SRE1 (3). The SREBF1 proteins are important in the regulation of genes involved in lipid metabolism, while SREBF2 has been more closely associated with cholesterol synthesis and accumulation (4).

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Catalog Number: (10014-482)

Supplier: Enzo Life Sciences

Description: Immunoglobulin G (IgG) is an immunoglobulin monomer consisting of two (gamma) heavy chains and two light chains. Each IgG molecule contains two antigen binding domains and a single effector (Fc) domain.

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Catalog Number: (75933-866)

Supplier: Rockland Immunochemical

Description: Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.

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Catalog Number: (89145-996)

Supplier: Enzo Life Sciences

Description: Host: Goat

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Catalog Number: (75933-790)

Supplier: Rockland Immunochemical

Description: Flavin-dependent histone demethylases regulate histone lysine methylation, an epigenetic mark that regulates gene expression and chromatin function (reviewed in 1). KDM1B is a recently identified histone H3K4 demethylase that is required to establish maternal genomic imprints; targeted disruption of the KDM1B gene in mice led to lethality in their embryos, suggesting demethylation of H3K4 is critical for establishing the DNA methylation imprints (2). KDM1B has also been shown to play a role in the transcription elongation in several genes (3).

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Supplier: Diagnostic Biosystems

Description: The catenins are structurally related cytoplasmic proteins which have been classified as alpha (α), beta (β), and gamma (γ), these proteins can bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. β-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule.

Catalog Number: (RL100-4167C)

Supplier: Rockland Immunochemical

Description: Anti-IkBa Antibody is suitable for western blotting, ELISA, and IHC. Researchers should determine optimal titers for applications that are not stated below.

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Catalog Number: (RL607-1202)

Supplier: Rockland Immunochemical

Description: Secondary Goat Anti-IgG (H&L) Reacts with Hamster

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Catalog Number: (76002-468)

Supplier: Enzo Life Sciences

Description: Recommended Applications: Flow Cytometry, WB, FUNC

Species reactivity: Human

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Catalog Number: (89146-094)

Supplier: Enzo Life Sciences

Description: Host: Rabbit

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Catalog Number: (101106-532)

Supplier: Enzo Life Sciences

Description: Cyclic AMP (cAMP) is one of the most important second messenger involved as a modulator of physiological processes. A number of hormones are known to activate cAMP through the action of the enzyme Adenylate cyclase which converts ATP to cAMP. cAMP has been shown to be involved in the cardiovascular and nervous systems, immune mechanisms, cell growth and differentiation, and general metabolism.

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