AS601245 ≥95%, Moligand™

Supplier: ALADDIN SCIENTIFIC

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ALA275935-5MGEA 112.01 USD

ALA275935-5MG ALA275935100MG ALA275935-10MG ALA275935-1MG ALA275935-25MG ALA275935-50MG

AS601245 ≥95%, Moligand™

AS601245

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.Product Introduction:A cell-permeable pyrimidinyl compound that displays anti-inflammatory properties. Acts as a potent, reversible, and ATP-competitive inhibitor of c-Jun N-terminal kinase (JNK, IC50 = 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3, respectively) with a 10- to 100-fold greater selectivity over a panel of 25 other commonly studied kinases (IC50 typically in the range of 1-10 µM or no effect at 10 µM). Its in vivo efficacy has been demonstrated in gerbils, mice, and rats via oral, i.v., or i.p. administration. Biochemical mechanism:Cell permeable: yesProduct competes with ATP.Primary TargethJNK 1, hJNK 2, hJNK 3Reversible: yesTarget IC50: 150, 220, and 70 nM for hJNK1, hJNK2, and hJNK3, respectively

Formula: C₂₀H₁₆N₆S
MW: 372.45 g/mol
Storage Temperature: Freezer

MDL Number: MFCD07772196
CAS Number: 345987-15-7

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