Staurosporine (from Streptomyces species), Sigma-Aldrich®
Supplier: EMD MILLIPORE (BIOSCIENCES)
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Avg. Ratings: 0.0 out of 5
569397-100UG
569397-250UG
569397-1MG
80057-524EA
239.04
USD
80057-524
80057-526
82603-680
Staurosporine (from Streptomyces species), Sigma-Aldrich®
Staurosporine
A potent cell-permeable broad spectrum inhibitor of protein kinases
Inhibits CaM kinase (IC50=20nM), myosin light chain kinase (IC50=1.3nM), protein kinase A (IC50=7nM), protein kinase C (IC50=0.7nM), and protein kinase G (IC50=8.5nM). Also inhibits platelet aggregation induced by collagen or ADP but has no effect on thrombin-induced platelet aggregation. Induces apoptosis in human malignant glioma cell lines. Arrests normal cells at the G1 checkpoint.
Formula:
C₂₈H₂₆N₄O₃ MW: 466.541 g/mol |
MDL Number:
MFCD18252446 CAS Number: 62996-74-1 |
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