Anti-CDX2 Rabbit Monoclonal Antibody [clone: EP25]

Supplier: Diagnostic Biosystems
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RMAB059-05-RUO RMAB059 RMAB059-01
76634-786EA 632 USD
76634-786 76634-788 76634-784
Anti-CDX2 Rabbit Monoclonal Antibody [clone: EP25]
Antibodies
The caudal-related homeodomain protein 2, CDX-2, is a transcription factor which is expressed in the intestine and is thought to play an important role in the proliferation and differentiation of intestinal epithelial cells. The CDX-2 protein is expressed in primary and metastatic colorectal carcinomas, intestinal metaplasia of the stomach and intestinal type gastric cancer. In human colorectal cancer, the expression of both CDX2 and carbonic anhydrase 1, a gene regulated by CDX2, is reduced or absent. CDX-2 is one of the important regulators in defining pathways for coordinate control of drug metabolism in the gastrointestinal tract.
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