DMP (Dimethyl pimelimidate dihydrochloride), Pierce™

Supplier: Paul Schöndorf Metallwaren GmbH
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PI21666EA 84.31 USD
PI21666 PI21667
DMP (Dimethyl pimelimidate dihydrochloride), Pierce™
DMP (Dimethyl pimelimidate dihydrochloride)

Thermo Scientific Pierce DMP is dimethyl pimelimidate, a membrane-permeable crosslinker that contains an amine-reactive imidoester group at each end of a 7-atom spacer arm.


  • Reactive groups: imidoester (both ends)
  • Reactive towards: amino groups (primary amines)
  • Mid-length reagent of three similar imidoester crosslinkers, which include DMA, DMP and DMS
  • Water-soluble
  • Imidoesters react with amines at alkaline pH values (pH 8-10) to form amidine bond
  • Amidine bond retains net charge character of protein primary amine to which it reacts
  • Reversible at high pH values
  • Tool for study of quarternary structure of proteins


Caution: For Research Use Only. Not for use in diagnostic procedures.

Formula: C₉H₁₈N₂O₂
MW: 259.17 g/mol
Storage Temperature: Refrigerator
MDL Number: MFCD00038942
CAS Number: 58537-94-3

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Specification Test Results

Product Line Pierce™
Labeling Method Chemical Labeling
Crosslinker Type Homobifunctional
Reactive Moiety Imidoester
Spacer Short
Form Powder
Quantity 50 mg
Type Crosslinker
Solubility Water
Spacer Arm 9.2 Å


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