Calcimycin (A23187)

Supplier: Bioanalytic

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Calcium ionophore Calcimycin

Calcium Ionophore Calcimycin

Calcium Ionophore Calcimycin

Calcium ionophore Calcimycin

Calcium Ionophore Calcimycin

Calcium Ionophore Calcimycin

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A20480-0.005 A20480-0.025

76344-768EA 152.42 USD

76344-768 76344-770

Calcimycin (A23187)

Calcimycin (A23187)

Calcium ionophore is a commonly used Ionophone Antibiotic that increases intracellular Ca2+ in intact cells and forms stable 2:1 complexes with divalent cations.

It acts as an uncoupler of oxidative phosphorylation and inhibits mitochondrial ATPase activity.
It can also induce Apototosis in mouse Lymphoma cell line S49.
However, it is shown to block Apotosis in other systems such as when Interleukin-3 (IL-3) is withdrawn from IL-3 dependent cells.
Supplied as dry powder.

Formula: C₂₉H₃₇N₃O₆
Melting Pt: 182 …193 °C
Storage Temperature: Freezer

MDL Number: MFCD00151202
CAS Number: 52665-69-7
EINECS: 258-084-1

Specification Test Results

Appearance	White crystalline powder
Identification (UV)	Conforms
Lambda Max	Report nm
Melting Point	189 - 190 oC
Solubility	10 mg/ml soluble in Methylene Chloride

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