Indo-1 AM ≥96% (by HPLC) fluorescent indicator, for calcium determination

Supplier: BIOTIUM, INC

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Indo-1 AM ≥96% (by HPLC) fluorescent indicator, for calcium determination

Indo-1 AM

Indo-1, AM ester is membrane-permeant and thus can be loaded into cells via incubation. Because of the relatively low water solubility of the AM ester, Pluronic F-127, a mild detergent, is often used as a dispersing agent to facilitate cell loading. Indo-1-AM Ester itself does not bind Ca2+ , but it is readily hydrolyzed to indo-1 by endogenous esterases once it enters cells.

Absorption/Emission 356 nm/478 nm (no Ca2+); 330 nm/400 nm (high Ca2+)
Extinction Coefficient 33,000 M -1 cm -1 (no Ca2+); 33,000 M -1 cm -1 (high Ca2+)
Cell permeability: Membrane permeant
Light yellow solid soluble in DMSO
Store desiccated at -20°C and protect from light, especially in solution

Formula: C₄₇H₅₁N₃O₂₂
Storage Temperature: Freezer

MDL Number: MFCD00036955
CAS Number: 112926-02-0

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