Human Recombinant IL-1-alpha

Supplier: Bandelin Electronic GmbH &Co.KG

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009-001-V24-0010 009-001-V24-0100

75929-108EA 137.15 USD

75929-108 75934-718 75934-720 75934-722

Human Recombinant IL-1-alpha

Proteins and Peptides

Recombinant Human IL-1-alpha control protein

Control Protein
PCA Assays
ImmunoBlot

Interleukin-1 alpha (IL-1α) is constiutively expressed by epithlial cells, but can also be produced by most other cells upon stimulation. IL-1β and IL-1α are two distinct and independently regulated gene products that comprise IL-1 and signal through the Type 1 IL-1 receptor (IL-1R1). Although IL-1α is cell associated and IL-1β is secreted, they have nearly identical biological activity in that they induce adhesion molecule expression on epithelial cells, control fever induction, and play a role in arthritis and septic shock. Signaling activated by the IL-1R1 promotes these activities through a MYD88 signaling pathway similar to those associated with Toll receptors. Recombinant human IL-1α is a non-glycosylated single chain protein, containing 159 amino acids, with a molecular weight of 18 kDa.

Interleukin-1-alpha Recombinant Protein is suitable as a control for polyclonal or monoclonal anti-Interleukin-1-alpha in immunological assays.

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