3M™ Emphaze™ AEX Series Hybrid Purifiers, 3M

Supplier: SOLVENTUM PURIFICATION INC
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7100048384 7100179206 7100174193 EMP301AEX020R 7100158434 7100158416 7100166976 7100158435 7100158436 7100158437
76046-986CS 11253.05 USD
76046-986 76407-176 76407-178 76407-180 76407-182 76407-184 76407-186 76407-188 76436-434 76436-436
3M™ Emphaze™ AEX Series Hybrid Purifiers, 3M
Filters Capsule Filters
3M™ Emphaze AEX Hybrid Purifier is our single-use sterilisable and sanitisable. The all-synthetic purification media that contains a Q-functional anion exchange media and a fine particle and bioburden reduction membrane.

  • Contains highly functionalized media
  • Excellent throughput and mAb recovery (often equal to or greater than 95%)
  • Enhanced capture column performance and protection
  • Substantial turbidity, DNA, HCP and bioburden reduction
  • Reduced surface area requirement of the downstream sterilizing grade membrane
  • May offer differentiated protection of the protein A column for enhanced contaminant clearance performance
  • Capsule compatibility is based on testing with 1M NaOH and 5% NaClO (bleach)

Remove impurities in biopharmaceutical process streams such as DNA, host cell proteins (HCP) and viruses with our all-synthetic, single use 3M™ Emphaze AEX Hybrid Purifier. The composite purification media is comprised of three primary components: anion exchange nonwoven, microporous membrane, and membrane support. The anion exchange media is composed of four layers of polypropylene nonwoven with a covalently attached quaternary ammonium functional polymer.

The bioburden reduction membrane is a highly asymmetric polyamide membrane which has nine zones of decreasing pore size, spanning approximately a 20 × range, and terminating with a 0.2 μm rated qualifying layer. This is followed by a polypropylene nonwoven used as a support layer in the capsule.

Capsules
There are two primary capsule configurations for the Emphaze AEX Hybrid Purifier, Laboratory and Scale-up capsules:
- The Laboratory capsule (BV8) has an 8 ml bed volume
- The Scale-up capsules are constructed from a lenticular media cell design having bed volumes of 120 and 360 ml (BV 120 and BV 360 respectively)
- The Production capsules are scaled to meet your manufacturing requirements and utilise manifolds in a holder for ease of use

Certifications: All product components comply with United States Pharmacopeia (USP) <88> Class VI 70 °C Biological Reactivity Tests, in-vivo.

Ordering information: A full support package is available for 3M Emphaze AEX Hybrid Purifiers. This package includes Installation and Operation Guides, a Certificate of Quality and a Regulatory Support File.
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