5-Aminolevulinic acid hydrochloride 98-102%
Supplier: Hansa Fine Chemicals GmbHTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
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Warning
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Synonyms:
5-Amino-4-ketovaleric acid hydrochloride, 5-Amino-4-oxopentanoic acid hydrochloride, δ-Aminolevulinic Acid Hydrochloride
5-Aminolevulinic acid hydrochloride is a δ-amino acid and be used as bronsted acid.
5-Aminolevulinic acid hydrochloride is used as antitumor agents, phototherapy, antinematodal drug, photosensitizing agent, dermatologic drug and prodrug. It is also used in photodynamic therapy of actinic keratosis, porphobilinogen synthase substrate that produces endogenous porphyrins useful for sensitizing cells in photodynamic therapy, intermediate in heme and chlorophyll biosynthesis, estimation of 5-aminolevulinic acid dehydratase.
PBG formed in the assay can be determined spectrophotometrically with Ehrlich's reagent, used in porphyrin test for differentiation of haemophilus species, enzymes that convert ALA to porphyrins in the biosynthesis of hemin (X factor) are not produced by H. influenzae, H. aegyptius and H. canis. These enzymes are produced by H. parainfluenzae, H. parahaemolyticus, H. gallinarum, H. parasuis, H. parahaemolyticus and H. aphrophilus. A positive reaction is indicated by an orange-red fluorescence.
It plays important biological role as metabolite, saccharomyces cerevisiae metabolite, plant metabolite, E. coli metabolite and human metabolite.
Synonyms: delta-Aminolevulinic acid hydrochloride; 5-Amino-4-oxopentanoic acid HCl; ALA.HCl
Formula:
C₅H₁₀ClNO₃ MW: 167.59 g/mol Storage Temperature: Low Temperature Freezer (–40°C) |
MDL Number:
MFCD00012869 CAS Number: 5451-09-2 EINECS: 226-679-5 |
Specification Test Results
Turbidity (NTU) | Max. 2.0 |
Water Content | Max. 1.0% |
Loss on Drying (105 °C, 3 hr, Vacuum) | Max. 2% |
Sulphated Ash | Max. 0.1% |
Argentometric Titration | 98.0 – 102.0% |
TLC (Butanol/Acetic Acid/Water 3:1:1; Ninhydrin) | Corresponds to Reference Material |
Residual Solvents | Sum of 2-Propanol and Acetone Max. 0.5% |
FT-IR Spectrum | Corresponds to Reference Spectrum |
Recommended Retest Period | 36 Months |
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