Acetonitrile 99,9, Liquid_clear HPLC, Spectroscopy

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76180-708EA 619.04 USD
76180-708 76180-712
Acetonitrile 99,9, Liquid_clear HPLC, Spectroscopy
Acetonitrile

This colourless liquid is the simplest organic nitrile (hydrogen cyanide is a simpler nitrile, but the cyanide anion is not classed as organic). It is produced mainly as a byproduct of acrylonitrile manufacture.
Acetonitrile is widely used as a polar aprotic solvent in organic synthesis and in the purification of butadiene in refineries.
This solvent is often the preferred choice as a mobile phase in HPLC for a variety of reasons. Not only is it miscible with water and with many other organic solvents, but it also has a lower viscosity and produces less pressure in the column than other solvents such as Methanol. The inherent low absorbance of Acetonitrile (especially HPLC grade) makes it the preferred solvent for the mobile phase of HPLC due to the reduction in the amount of noise during UV detection. Overall, Acetonitrile has many unique properties as an organic mobile phase that often result in better chromatographic peaks.
Acetonitrile also plays an important role as the main solvent used in the manufacture of DNA oligonucleotides from monomers.
Room Temperature, store under nitrogen.


  • HPLC/Spectro Grade
  • Auto Ignition: 524 °C (Lit.)
  • Vapor Density: 1.4 (air = 1) (Lit.)
  • Vapor Pressure: 94.51 - 98.64 hPa at 20 °C (Lit.)
  • Refractive Index: n20/D 1.344(lit.)
  • Presentation: Clear Liquid
  • Soluble in water.

Formula: H₃CCN
MW: 41.05 g/mol
Boiling Pt: 81.6 (lit.)
Melting Pt: -45.7 (lit.)
Flash Pt: 2
Storage Temperature: Ambient
MDL Number: MFCD00001878
CAS Number: 75-05-8
UN: 1648
ADR: 3 II
Merck Index: 13,00071
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Specification Test Results

Identity Test Passes
Purity ≥99.9%
Residue after Evaporation ≤2 ppm
Water ≤0.02%
OD190 ≤1.00
OD200 ≤0.05
OD210 ≤0.04
OD220 ≤0.02
OD230 ≤0.01
OD254 ≤0.005
OD400 ≤0.005
Color (APHA) ≤10
LC Gradient Elution Suitability Passes
Titrable Acid ≤0.008 meq/g
Titrable Base ≤0.0006 meq/g


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