EGTA (ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid) ≥97% for molecular biology

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0219482310 0219482325 0219482380
IC0219482310EA 122.34 USD
IC0219482310 IC0219482325 IC0219482380
EGTA (ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid) ≥97% for molecular biology
EGTA (Ethylene glycol bis(2-aminoethyl ether)-N,N,N',N'-tetraacetic acid)

Physical Appearance: White Powder
pKa: < 2, 2.7, 8.8, and 9.5 (Lit.)
Solubility: Soluble in alkaline solutions (1 g in 10 mL 1 N NaOH + 50 mL water-clear, colorless solution).
Typical Working Concentration: as a metalloprotease inhibitor (effective concentration is typically 1 to 10 µM)
Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent. It is an inhibitor of alkaline phosphatase activity which is useful in ELISA reactions.
Ethylene Glycol-bis-(beta-aminoethylether)-N,N,N',N'-tetraacetic Acid is a chelating agent for determination of calcium in the presence of magnesium; it can also detect cadmium in the presence of zinc. It is also useful for the removal of heavy metal ions in biological systems. It is shown to activate Ca2+- stimulated ATPase in rat liver plasma membranes and induce apoptosis in PC12 cells. It also inhibits the zinc-dependent endopeptidases, matrix metalloproteinases.

Formula: C₁₄H₂₄N₂O₁₀
Melting Pt: 235…245 °C
MDL Number: MFCD00004291
CAS Number: 67-42-5
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