Human Beta-Amyloid (1-42)

Supplier: Hytest Ltd

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AS-60883 AS-60883-01

103006-096EA 695.69 USD

103006-096 103006-098

Human Beta-Amyloid (1-42)

Proteins and Peptides

This peptide prepared by neutralizing the TFA salt form of Aß (1-42) with a dilute sodium hydroxide solution has superior solubility and fibrillogenesis properties, and the fibrils are equally neurotoxic.
Sequence: DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIA
MW: 4514.1+23 Da
Molecular Weight: 4514.1 + 23
% Peak Area by HPLC: ≥95
Peptide Content: ≥ 60%
Storage condition: -20°C

Citations:
Luo, W. et al. (2011). Synthesis and biological evaluation of novel N,N′-bis-methylenedioxybenzyl-alkylenediamines as bivalent anti-Alzheimer disease ligands. J Enzyme Inhibition Med Chem doi:10.3109/14756366.2010.548329.

Nakagami,Y. et al. (2002). A novel β-sheet breaker, RS-0406, reverses amyloid β-induced cytotoxicity and impairment of long-term potentiation in vitro. Br J Pharmacol 137, 676. doi: 10.1038/sj.bjp.0704911.

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