Human beta-Amyloid (1-42)

Supplier: Hytest Ltd

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AS-21791 AS-21793

102996-168EA 507.15 USD

102996-168 102996-170

Human beta-Amyloid (1-42)

Proteins and Peptides

This is a salt form of Aβ(1-42) known to form aggregates within a few days in water or recommended solvents. The salt form has been found to form fibrils, exerts cytotoxicity in neuronal models and so, used in studies that evaluate activity of agents that reverse amyloid-induced cytotoxicity.

Peptide Content: ≥60%

Citations:
Iwasaki, K. et al. (2007). Nilvadipine prevents the impairment of spatial memory induced by cerebral ischemia combined with β-amyloid in rats. Biol Pharm Bull 30, 698.
Iwasaki, K. et al. (2006). Cerebral ischemia combined with β-amyloid impairs spatial memory in the eight-arm radial maze task in rats. Brain Res 1097, 216. doi: 10.1016/j.brainres.2006.04.073.
Hirata, K. et al. (2005). A novel neurotrophic agent, T-817MA [1-{3-[2-(1-Benzothiophen-5-yl) Ethoxy] Propyl}-3-azetidinol Maleate], attenuates amyloid-β-induced neurotoxicity and promotes neurite outgrowth in rat cultured central nervous system neurons. JPET 314, 252. doi: 10.1124/jpet.105.083543.

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