Human Recombinant BDNF (from E. coli)

Supplier: PEPROTECH INC.
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AF-450-02-2UG AF-450-02-10UG AF-450-02-100UG AF-450-02-250UG AF-450-02-500UG AF-450-02-1MG
10781-784EA 181.47 USD
10781-784 10781-786 10781-788 10781-790 10781-792 10781-794
Human Recombinant BDNF (from E. coli)
Proteins and Peptides

BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues. Recombinant Human BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions. Human and Mouse BDNF sequences are identical. Manufactured using all Animal-Free reagents.


  • Carrier free
  • Animal-free


MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR


Verified by N-terminal and Mass Spectrometry analyses (when applicable).


Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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