Human Recombinant PDGF-BB (from E. coli)

Supplier: PEPROTECH INC.
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AF-100-14B-2UG AF-100-14B-10UG AF-100-14B-100UG AF-100-14B-250UG AF-100-14B-500UG AF-100-14B-1MG
10781-680EA 181.47 USD
10781-680 10781-682 10781-684 10781-686 10781-688 10781-690
Human Recombinant PDGF-BB (from E. coli)
Proteins and Peptides

PDGFs are disulfide-linked dimers consisting of two 12.0-13.5 kDa polypeptide chains, designated PDGF-A and PDGF-B chains. The three naturally occurring PDGFs, PDGF-AA, PDGF-BB and PDGF-AB, are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and some blood cells. The PDGFs are stored in platelet α-granules, and are released upon platelet activation. The PDGFs are involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. Two distinct signaling receptors used by PDGFs have been identified and named PDGFR-α and PDGFR-β. PDGFR-α is a high-affinity receptor for each of the three PDGF forms. On the other hand, PDGFR-β interacts with only PDGF-BB and PDGF-AB. Recombinant Human PDGF-BB is a 24.3 kDa disulfide-linked homodimer of two β chains (218 total amino acids).


  • Animal-free


Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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