Human;Mouse;Rat Recombinant BDNF (from E. coli)

Supplier: PEPROTECH INC.

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10781-152EA 143.4 USD

10781-152 10781-154 10781-156 10781-158 10781-160 10781-162 10781-164

Human;Mouse;Rat Recombinant BDNF (from E. coli)

Proteins and Peptides

BDNF is a member of the NGF family of neurotrophic growth factors. Like other members of this family, BDNF supports neuron proliferation and survival. BDNF can bind to a low affinity cell surface receptor called LNGFR, which also binds other neurotrophins such as NGF, NT-3 and NT-4. However, BDNF mediates its neurotrophic properties by signaling through a high affinity cell surface receptor called gp145/trkB. BDNF is expressed as the C-terminal portion of a 247 amino acid polypeptide precursor, which also contains a signal sequence of 18 amino acid residues and a propeptide of 110 amino acid residues. Recombinant Human/Murine/Rat BDNF is a 27.0 kDa homodimer of two 120 amino acid subunits linked by strong non-covalent interactions.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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