Human Recombinant MMP-2 (from E. coli)

Supplier: PEPROTECH INC.

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10781-116EA 132.81 USD

10781-116 10781-118 10781-120 10781-122 10781-124 10781-126 10781-128

Human Recombinant MMP-2 (from E. coli)

Proteins and Peptides

Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-2 is a secreted collagenase with specificity toward Type IV, V, VII, and X collagens. Recombinant Human MMP-2 is a 62.0 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (552 amino acids).

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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