Rat Recombinant MIP-1 Beta (from E. coli)

Supplier: PEPROTECH INC.
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10780-950EA 132.81 USD
10780-950 10780-952 10780-954 10780-956 10780-958 10780-960
Rat Recombinant MIP-1 Beta (from E. coli)
Proteins and Peptides

Both MIP-1α and MIP-1β are structurally and functionally related CC chemokines. They participate in host response to invading bacterial, viral, parasite and fungal pathogens, by regulating the trafficking, and activation state, of selected subgroups of inflammatory cells (e.g. macrophages, lymphocytes and NK cells). While both MIP-1α and MIP-1β exert similar effects on monocytes, their effect on lymphocytes differ; with MIP-1α selectively attracting CD8+ lymphocytes, and MIP-1α selectively attracting CD4+ lymphocytes. Additionally, MIP-1α and MIP-1β have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells. Both human and murine MIP-1α and MIP-1β are active on human and murine hematopoietic cells. Recombinant Rat MIP-1β (CCL4) is a 7.8 kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.


Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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