Human Recombinant IL-36gamma (from E. coli)

Supplier: PEPROTECH INC.

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Avg. Ratings: 0.0 out of 5

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10779-892EA 143.88 USD

10779-892 10779-894 10779-896 10779-898 10779-900 10779-902

Human Recombinant IL-36gamma (from E. coli)

Proteins and Peptides

The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36 α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36γ is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36γ signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36γ also functions as an agonist of NF-κB, and can stimulate the inflammatory response in bronchial epithelial cells. Recombinant Human IL-36γ (IL-1F9) is a 17.0 kDa protein containing 152 amino acid residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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