Human Recombinant IL-23 (from (BTI-Tn-5B1-4) Hi-5 Insect Cells)

Supplier: PEPROTECH INC.

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10779-764EA 143.41 USD

10779-764 10779-766 10779-768 10779-770 10779-772 10779-774 10779-776

Human Recombinant IL-23 (from (BTI-Tn-5B1-4) Hi-5 Insect Cells)

Proteins and Peptides

IL-23 is a proinflammatory, heterodimeric protein composed of two subunits: a unique p19 subunit, and a p40 subunit that is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages, and signals though a receptor comprised of IL-23R complexed with IL-12Rβ2. IL-23 has been shown to enhance proliferation of memory T cells. It also stimulates the production of IFN-γ in NK cells, induces IL-17 production, and drives Th17-mediated responses. Recombinant Human IL-23 is a 53.5 kDa, heterodimeric protein consisting of the two subunits, p19 (170 amino acids) and p40 (306 amino acids).

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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