Rat Recombinant IL-13 (from E.coli)

Supplier: PEPROTECH INC.

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10774-512EA 143.88 USD

10774-512 10774-514 10774-516 10774-518 10774-520 10774-522

Rat Recombinant IL-13 (from E.coli)

Proteins and Peptides

IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 are cross-species reactive. Recombinant Rat IL-13 a 12.3 kDa protein consisting of 113 amino acid residues.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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