Human Recombinant IGF-BP6 (from (BTI-Tn-5B1-4) Hi-5 Insect cells)

Supplier: PEPROTECH INC.

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10774-452EA 139.89 USD

10774-452 10774-454 10774-456 10774-458 10774-460 10774-462

Human Recombinant IGF-BP6 (from (BTI-Tn-5B1-4) Hi-5 Insect cells)

Proteins and Peptides

IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6, which specifically inhibits IGF-II actions, is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma. Recombinant Human IGF-BP6 has a calculated mass of 22.3 kDa and consists of 213 amino acid residues, including the IGF-BP domain and thyroglobulin type-I domain. Recombinant Human IGF-BP6 migrates at an apparent molecular weight of approximately 23.0-30.0 kDa by SDS-PAGE analysis under non-reducing conditions.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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