Human Recombinant TNF-beta (from E. coli)

Supplier: PEPROTECH INC.

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10773-462EA 132.81 USD

10773-462 10773-464 10773-466 10773-468 10773-470 10773-472 10773-474

Human Recombinant TNF-beta (from E. coli)

Proteins and Peptides

TNF-β is a potent mediator of inflammatory and immune responses. It belongs to the TNF family of ligands, and signals through TNFR1 and TNFR2. TNF-β is produced by activated T and B lymphocytes, and has similar activities to TNF-α. Like TNF-α, TNF-β is involved in the regulation of various biological processes, including cell proliferation, differentiation, apoptosis, lipid metabolism, coagulation, and neurotransmission. TNF-β is secreted as a soluble polypeptide, but can form heterotrimers with lymphotoxin-β, which effectively anchors the TNF-β to the cell surface. TNF-β is cytotoxic to a wide range of tumor cells. Recombinant Human TNF-β is a secreted 172 amino acid protein (18.6 kDa) which forms an active non-disulfide-linked homotrimer structure in solution.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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