Human Recombinant ANGPTL-3 (from CHO cells)

Supplier: PEPROTECH INC.
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10772-812EA 143.88 USD
10772-812 10772-814 10772-816 10772-818 10772-820 10772-822
Human Recombinant ANGPTL-3 (from CHO cells)
Proteins and Peptides

ANGPTL-3 (Angiopoietin-like protein 3) is a member of the angiopoietin family of structurally related proteins, characterized by a coiled N-terminal domain and a C-terminal fibrinogen-like domain. It is primarily expressed in the liver, and can exert activities related to both angiogenesis and lipid metabolism. ANGPTL-3 inhibits lipoprotein lipase (LPL) and endothelial lipase (EL), which has the effect of increasing plasma levels of triglycerides and HDL-associated cholesterol. The fibrinogen-like portion of the ANGPTL-3 protein can bind alpha-5/beta-3 integrins, leading to endothelial cell adhesion and migration. Recombinant Human ANGPTL-3 is a glycoprotein that migrates by SDS-PAGE analysis at an apparent molecular weight of 62 kDa, and contains 452 amino acid residues including a C-terminal His tag. The calculated molecular weight of Recombinant Human ANGPTL-3 is 52.9 kDa.


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