Human Recombinant Follistatin (from E. coli), PeproTech

Supplier: PEPROTECH INC.

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10772-492EA 132.81 USD

10772-492 10772-494 10772-496 10772-498 10772-500 10772-502

Human Recombinant Follistatin (from E. coli), PeproTech

Proteins and Peptides

Follistatin is a secreted protein that binds to ligands of the TGF-β family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as an activin antagonist whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-β ligands including BMP-2,-4,-6,-7, Myostatin, GDF-11, and TGF-β1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant Human Follistatin is a 31.5 kDa protein containing 288 amino acids. Its primary structure contains three cysteine-rich domains (called FS domains), each followed by a protease-inhibitory kazal domain.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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