Human Recombinant sCD14 (from HEK293 Cells)

Supplier: PEPROTECH INC.

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10772-314EA 341.45 USD

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Human Recombinant sCD14 (from HEK293 Cells)

Proteins and Peptides

CD14 is a cell surface-anchored glycoprotein that is expressed predominantly by monocytes and tissue macrophages. CD14 associates with MD-2 (LY-96) and TLR4 to form a receptor complex, which signals specifically in response to bacterial lipopolysaccharide (LPS) binding. The CD14/MD-2/TLR4 receptor complex signals via MyD88, TIRAP, and TRAF6, and ultimately activates NF-κB. CD14 also exists in a soluble form, designated as sCD14, which is capable of specifically binding LPS in the extracellular space. Recombinant Human sCD14 is a 331 amino acid glycoprotein comprising the extracellular portion of the CD14 receptor. The calculated molecular weight of Recombinant Human sCD14 is 35.6 kDa.

Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.

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