Anti-CD19 Rat Monoclonal Antibody (Biotin) [clone: 1D3]

Supplier: Tonbo Biosciences

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C57Bl/6 splenocytes were stained with 0.125 ug Anti-Mouse CD19 Biotin (30-0193) (solid line) or 0.125 ug Rat IgG2a Biotin isotype control (dashed line), followed by Streptavidin PE.

C57Bl/6 splenocytes were stained with 0.125 ug Anti-Mouse CD19 Biotin (30-0193) (solid line) or 0.125 ug Rat IgG2a Biotin isotype control (dashed line), followed by Streptavidin PE.

30-0193-U025 30-0193-U100 30-0193-U500

10050-752EA 39.6 USD

10050-752 10050-754 10050-756

Anti-CD19 Rat Monoclonal Antibody (Biotin) [clone: 1D3]

Antibodies

The 1D3 antibody reacts with mouse CD19, a 95 kDa glycoprotein which acts as a co-receptor, along with CD21 and CD81, in support of the functional B cell receptor (BCR). This complex provides antigen-specific recognition and subsequent activation of B cells to proliferate and differentiate into antibody-secreting cells (plasma cells) or memory B cells, which are crucial for secondary antigen encounter. CD19 is a lineage-differentiation marker, as its expression is detectable at the earliest B cell stages, through development, and is finally lost upon transition to mature plasma cells.

The 1D3 antibody is widely used as a phenotypic marker for CD19 expression on B cells, as well as on dendritic cell subsets.

Type: Primary
Antigen: CD19 (CD19 molecule)
Clonality: monoclonal
Clone: 1D3
Conjugation: Biotin
Epitope:
Host: Rat
Isotype: IgG2a Kappa
Reactivity: Mouse

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