Anti-TNFSF4 Rat Monoclonal Antibody (Biotin) [clone: RM134L]

Supplier: Tonbo Biosciences

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C57Bl/6 splenocytes were stimulated with anti-IgM and anti-CD40 for 4 days. Cells were then stained with 0.5 ug Biotin Anti-Mouse CD252 (30-5905) (solid line) or 0.5 ug Biotin Rat IgG2b isotype control (dashed line), followed by Streptavidin PE.

C57Bl/6 splenocytes were stimulated with anti-IgM and anti-CD40 for 4 days. Cells were then stained with 0.5 ug Biotin Anti-Mouse CD252 (30-5905) (solid line) or 0.5 ug Biotin Rat IgG2b isotype control (dashed line), followed by Streptavidin PE.

30-5905-U025 30-5905-U100

10208-344EA 40.7 USD

10208-344 10208-346

Anti-TNFSF4 Rat Monoclonal Antibody (Biotin) [clone: RM134L]

Antibodies

The RM134L antibody recognizes CD252, also known as OX-40 Ligand or CD134 Ligand, a member of the TNF superfamily that is present on the surface of antigen presenting cells and activated B lymphocytes. The OX-40 Ligand interacts with OX-40 (CD134) which is expressed primarily on activated T cells. This costimulatory interaction leads to increased proliferation and IL-2 production responses of activated T cells, and at the same time enhances proliferation and immunoglobulin secretion by activated B cells.

The RM134L antibody is useful for flow cytometric detection of CD252 on stimulated mouse splenocytes. It has also been reported to block the costimulatory activity of OX-40 Ligand. Please choose the appropriate format for each application.

Type: Primary
Antigen: TNFSF4
Clonality: Monoclonal
Clone: RM134L
Conjugation: Biotin
Epitope:
Host: Rat
Isotype: IgG2b kappa
Reactivity: Mouse

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