Anti-CD80 Armenian Hamster Monoclonal Antibody (APC (Allophycocyanin)) [clone: 16-10A1]

Supplier: Tonbo Biosciences

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C57Bl/6 splenocytes were stimulated with anti-IgM and anti-CD40 for 4 days. Cells were then stained with 0.06 ug APC Anti-Mouse CD80 (20-0801) (solid line) or 0.06 ug APC Armenian Hamster isotype control (dashed line).

C57Bl/6 splenocytes were stimulated with anti-IgM and anti-CD40 for 4 days. Cells were then stained with 0.06 ug APC Anti-Mouse CD80 (20-0801) (solid line) or 0.06 ug APC Armenian Hamster isotype control (dashed line).

20-0801-U025 20-0801-U100

10210-114EA 66 USD

10210-114 10210-116

Anti-CD80 Armenian Hamster Monoclonal Antibody (APC (Allophycocyanin)) [clone: 16-10A1]

Antibodies

The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.

Type: Primary
Antigen: CD80
Clonality: Monoclonal
Clone: 16-10A1
Conjugation: APC (Allophycocyanin)
Epitope:
Host: Armenian Hamster
Isotype: IgG
Reactivity:

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