Cytochalasin B (from Helminthosporium dematioideum), white powder

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Cytochalasin B (from Helminthosporium dematioideum), white powder

Cytochalasin B

Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts.

Presentation: White Powder
Soluble in methanol (20 mg/mL - clear, colorless solution) or ethanol, DMSO (10 mg/mL), DMF; Insoluble in water.
Storage temperature: -20 °C, desiccate, protect from light.

Formula: C₂₉H₃₇NO₅

MDL Number: MFCD00077704
CAS Number: 14930-96-2

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