MOPS-Na, white powder

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Synonyms: Sodium 4-morpholin-1-ylpropylsulfonate, 3-(N-Morpholino)propanesulphonic acid sodium salt, Sodium 3-morpholinopropane-1-sulphonate, 3-(N-Morpholino)propanesulfonic acid sodium salt, Sodium 4-morpholin-1-ylpropylsulphonate, MOPS sodium salt

0219067025 0219067080 0219067083 0219067091
IC19067025EA 57.75 USD
IC19067025 IC19067080 IC19067083 IC19067091
MOPS-Na, white powder
MOPS-Na

MOPS is used as a biological buffer.


Soluble in water (to approximately 33% w/w - clear, colorless solution).


MOPS is a zwitterionic amino acid which acts as one of the "Good" buffers. It is a structural analog to MES; however, MOPS is a more suitable biological buffer than MES because the pH range is closer to pH 7.4. A buffer using MOPS free acid can be prepared by titrating the free acid with sodium hydroxide to the desired pH (pKa ± 1), using about a half-equivalent of NaOH.


A buffer using MOPS sodium salt can be made by mixing equimolar MOPS free acid and MOPS sodium salt solutions to attain a buffer of the desired pH. Titration of a solution of MOPS sodium salt with HCl results in a solution that will contain NaCl, so the ionic strength will be higher than appropriate for some applications. Concentrations higher than 20 mM should not be used with mammalian cell cultures.

Formula: C₇H₁₄NNaO₄S
MW: 231.25 g/mol
MDL Number: MFCD00064350
CAS Number: 71119-22-7

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Specification Test Results

pH 9.0 - 10.5(1% aq solution)
pka pKa-7.2 at 25 °C
Water Content ≤0.5%

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